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Summary of Significant Accounting Policies - Additional Information (Detail) (USD $)
3 Months Ended 12 Months Ended
Mar. 31, 2014
Candidate
Dec. 31, 2011
Dec. 31, 2013
Mar. 31, 2013
Dec. 31, 2012
Organization Consolidation And Presentation Of Financial Statements [Abstract]          
Number of VDA drug candidates tested 2        
Accumulated earnings (deficit) $ (241,138,000)   $ (238,508,000)    
Cash 24,735,000   7,005,000 4,562,000 4,946,000
Period of inspection of product 30 days        
Percentage payment on gross margin of distributor's sales 20.00%        
Cost-of-goods-sold   $ 0