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Commitments and Contingencies (Details Textual)
$ in Thousands, € in Millions
1 Months Ended 9 Months Ended
Aug. 29, 2020
ft²
Jul. 31, 2022
USD ($)
Employee
Jul. 31, 2021
EUR (€)
Jun. 30, 2021
ft²
Sep. 30, 2022
USD ($)
Sep. 30, 2021
USD ($)
Commitments And Contingencies [Line Items]            
Workforce reduction, percentage   67.00%        
Workforce reduction, number of employees | Employee   12        
Area of office facilities taken on lease | ft² 5,200          
Operating lease term 42 months          
Additional operating lease term 36 months          
Weighted-average discount rate 7.00%       7.00%  
Lease renewal option option to renew for an additional 36 month term at the then prevailing rental rate.          
Lessee, Operating Lease, Existence of Option to Extend [true false] true          
Area of additional office facilities taken on sublease | ft²       3,000    
Operating sublease term       29 months    
Lessee, Operating Sublease, Existence of Option to Extend [true false]       false    
Lessee, operating lease, assumptions and judgments, allocation of lease and nonlease component         The leases include real estate taxes and insurance, which is not a lease component and is not included in the lease obligation. In addition, common area maintenance charges are based on actual costs incurred and are a non-lease component that is not included in the lease obligation.  
Operating lease, cash paid for measurement of lease liabilities         $ 98 $ 52
Lease liability         $ 409  
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]         Accrued expenses and other liabilities  
Operating Lease, Liability, Noncurrent, Statement of Financial Position [Extensible List]         Operating lease liability, net of current portion  
Weighted-average remaining lease term         4 years 1 month 6 days  
One-time Termination Benefits            
Commitments And Contingencies [Line Items]            
Restructuring charges   $ 790        
General and Administrative Expense            
Commitments And Contingencies [Line Items]            
Rent expense         $ 94 $ 78
General and Administrative Expense | One-time Termination Benefits            
Commitments And Contingencies [Line Items]            
Restructuring charges   300        
Accrued Compensation And Employee Benefits            
Commitments And Contingencies [Line Items]            
Restructuring charges         $ 250  
Research and development | Patent Assignment Agreement | University Medical Center of Johannes Gutenberg University Mainz            
Commitments And Contingencies [Line Items]            
Potential upfront and milestone obligations and royalty obligations | €     € 1.6      
Research and development | One-time Termination Benefits            
Commitments And Contingencies [Line Items]            
Restructuring charges   $ 490