Share-based Compensation

3 Months Ended

Mar. 31, 2019

Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]

Share-based Compensation

(8) Share-based Compensation

For the three month periods ended March 31, 2019 and 2018, the Company recognized the following non-cash, share-based compensation expense in the statements of operations (in thousands):

	Three Months Ended March 31,
	2019		2018
Research and development	$	23	$	38
General and administrative		27		59
Total	$	50	$	97

Stock option transactions for the three month period ended March 31, 2019 under the Company’s stock incentive plans were as follows:

	Number of Options			Weighted Average Exercise Price		Weighted Average Remaining Contractual Term (in years)
Options outstanding at December 31, 2018		33,503		$	96.22		7.29
Granted		—			—
Exercised	—			—
Forfeited and cancelled		(222	)		1,579.97
Options outstanding at March 31, 2019		33,281		$	86.32		6.98
Options exercisable at March 31, 2019		28,487		$	93.61		6.85
Options vested and expected to vest		33,276		$	86.33		6.98