Share-based Compensation

9 Months Ended

Sep. 30, 2016

Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]

Share-based Compensation

(8) Share-based Compensation

For the three and nine month periods ended September 30, 2016 and 2015, the Company recognized the following non-cash, share-based compensation expense in the statements of operations (in thousands):

	Three Months Ended September 30,				Nine Months Ended September 30,
	2016		2015		2016		2015
Research and development	$	94	$	42	$	189	$	132
General and administrative		173		107		416		322
Total	$	267	$	149	$	605	$	454

Stock option transactions for the nine month period ended September 30, 2016 under the Company’s stock incentive plans were as follows:

	Number of Options			Weighted Average Exercise Price		Weighted Average Remaining Contractual Term (in years)
Options outstanding at December 31, 2015		161,278		$	18.30		6.97
Granted		442,300			3.31
Exercised	—			—
Forfeited and cancelled		(18,713	)		28.39
Options outstanding at September 30, 2016		584,865		$	6.64		9.02
Options exercisable at September 30, 2016		159,887		$	14.55		7.46
Options vested and expected to vest		583,904		$	6.65		9.02

Stock award transactions related to restricted stock units for the nine month period ended September 30, 2016 under the Company’s stock incentive plans were as follows:

	Number of Shares			Weighted Average Grant Date Fair Value
Restricted stock units outstanding at December 31, 2015		62,359		$	8.36
Granted		—			—
Vested and released		(29,486	)		8.78
Forfeited and cancelled		(471	)		4.69
Restricted stock units outstanding at September 30, 2016		32,402		$	8.02