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Property and Equipment (Details) (USD $)
In Thousands, unless otherwise specified
3 Months Ended
Mar. 31, 2013
Dec. 31, 2012
Components of Property and equipment    
Property and Equipment, Gross $ 508 $ 533
Less accumulated depreciation and amortization (486) (510)
Property and equipment, net 22 23
Computer equipment
   
Components of Property and equipment    
Estimated Life 3 years  
Property and Equipment, Gross 87 104
Lab equipment
   
Components of Property and equipment    
Estimated Life 5 years  
Property and Equipment, Gross 142 142
Furniture and fixtures
   
Components of Property and equipment    
Estimated Life 5 years  
Property and Equipment, Gross 85 93
Computer software
   
Components of Property and equipment    
Estimated Life 3 years  
Property and Equipment, Gross 176 176
Leasehold improvements
   
Components of Property and equipment    
Leasehold improvements Lesser of useful life or life of the lease  
Property and Equipment, Gross $ 18 $ 18