EX-12.1 5 dex121.htm STATEMENT REGARDING COMPUTATION OF RATIOS Statement regarding computation of ratios

Exhibit 12.1

 

Nuvelo, Inc.

Computation of Ratios of Earnings to Fixed Charges

(in thousands, except ratio)

 

     Years Ended December 31,
    

Six Months

Ended

June 30, 2004

  
     1999
     2000
     2001
     2002
     2003
    

Net Loss

    $ (18,547 )   $ (22,253 )   $ (36,472 )   $ (44,978 )   $ (50,187 )   $ (28,638 )

Add: Fixed charges

      1,141       1,580       3,580       4,529       4,356       2,872  
    
 
 
 
 
 

Earnings as defined

      (17,406 )     (20,673 )     (32,892 )     (40,449 )     (45,831 )     (25,766 )
    
 
 
 
 
 

Estimated interest component of rent

      451       709       2,689       3,287       2,664       1,187  

Interest expense (1)

      690       871       891       1,242       1,692       1,685  
    
 
 
 
 
 

Total fixed charges

    $ 1,141     $ 1,580     $ 3,580     $ 4,529     $ 4,356     $ 2,872  
    
 
 
 
 
 

Ratio (3)

      —         —         —         —         —         —    
    
 
 
 
 
 

 

(1) Includes amortization of debt issuance costs

 

(2) We have not included a ratio of earnings to combined fixed charges and preferred stock dividends because we do not have preferred stock outstanding

 

(3) Earnings (as defined) for the period were insufficient to cover fixed charges