EX-12.1 6 dex121.htm STATEMENT REGARDING COMPUTATION OF RATIOS Prepared by R.R. Donnelley Financial -- Statement regarding computation of ratios

EXHIBIT 12.1

 

Nuvelo, Inc.

Computation of Ratios of Earnings to Fixed Charges

(in thousands, except ratio)

 

     Years Ended December 31,
    

Nine Months
Ended

September 30,

2003

  
     1998
     1999
     2000
     2001
     2002
    

Loss from continuing operations before taxes

    $ (16,369 )   $ (18,547 )   $ (22,253 )   $ (36,472 )   $ (44,978 )   $ (40,797 )

Add: Fixed charges

      542       1,141       1,580       3,580       4,529       3,150  
    
 
 
 
 
 

Earnings as defined

    $ (15,827 )   $ (17,406 )   $ (20,673 )   $ (32,892 )   $ (40,449 )   $ (37,647 )
    
 
 
 
 
 

Estimated interest component of rent

    $ 366     $ 451     $ 709     $ 2,689     $ 3,287     $ 2,016  

Interest expense (1)

      176       690       871       891       1,242       1,134  
    
 
 
 
 
 

Total fixed charges

    $ 542     $ 1,141     $ 1,580     $ 3,580     $ 4,529     $ 3,150  
    
 
 
 
 
 

Ratio (3)

      —         —         —         —         —         —    
    
 
 
 
 
 
(1) Includes amortization of debt issuance costs
(2) We have not included a ratio of earnings to combined fixed charges and preferred stock dividends because we do not have preferred stock outstanding
(3) Earnings (as defined) for the period were insufficient to cover fixed charges