EX-12.1 6 f91330orexv12w1.txt EXHIBIT 12.1 EXHIBIT 12.1 Nuvelo, Inc. Computation of Ratios of Earnings to Fixed Charges (in thousands, except ratio)
Years Ended December 31, Three Months -------------------------------------------------------------------- Ended 1998 1999 2000 2001 2002 March 31, 2003 -------- -------- -------- -------- -------- -------------- Loss from continuing operations before taxes $(16,369) $(18,547) $(22,253) $(36,472) $(44,978) $(13,583) Add: Fixed charges 542 1,141 1,580 3,580 4,529 1,034 -------- -------- -------- -------- -------- -------- Earnings as defined (15,827) (17,406) (20,673) (32,892) (40,449) (12,549) ======== ======== ======== ======== ======== ======== Estimated interest component of rent 366 451 709 2,689 3,287 673 Interest expense (1) 176 690 871 891 1,242 361 -------- -------- -------------------------------------- -------- Total fixed charges $ 542 $ 1,141 $ 1,580 $ 3,580 $ 4,529 $ 1,034 ======== ======== ======== ======== ======== ======== Ratio(3) -- -- -- -- -- --
(1) Includes amortization of debt issuance costs (2) We have not included a ratio of earnings to combined fixed charges and preferred stock dividends because we do not have any preferred stock outstanding (3) Earnings (as defined) for the period were insufficient to cover fixed charges