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Summarized Quarterly Data (Unaudited) - Summary of Quarterly Results of Operations (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 6 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Jun. 30, 2018
Sep. 30, 2018
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Condensed Financial Information Disclosure [Abstract]                        
Net revenues       $ 15,183 $ 18,713 $ 17,186 $ 14,769          
Loss from operations $ (17,721) $ (22,225) $ (23,988) (9,887) (6,844) (6,830) (6,356) $ (46,213) $ (63,934) $ (89,064) $ (29,917) $ (23,683)
Net loss $ (33,892) $ (36,997) $ (26,233) $ (12,105) $ (10,872) $ (11,916) $ (11,451) $ (63,230) $ (97,122) $ (138,696) $ (46,344) $ (24,197)
Loss per common share, basic (usd per share) $ (1.04) $ (1.13) $ (0.81) $ (0.39) $ (0.35) $ (0.39) $ (0.37) $ (1.94) $ (2.98) $ (4.22) $ (1.50) $ (0.86)
Loss per common share, diluted (usd per share) $ (1.04) $ (1.13) $ (0.81) $ (0.39) $ (0.35) $ (0.39) $ (0.37) $ (1.94) $ (2.98) $ (4.22) $ (1.50) $ (0.86)