Stock-Based Compensation

3 Months Ended

Mar. 31, 2019

Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]

Stock-Based Compensation

Note 8 — Stock-Based Compensation

Total stock-based compensation expense was recognized in our Condensed Consolidated Statements of Operations as follows (in thousands):

	Three months ended March 31,
	2019		2018
Cost of goods sold	$	820	$	1,131
Research and development		16,623		12,094
General and administrative		7,942		6,724
Total stock-based compensation	$	25,385	$	19,949

During the three months ended March 31, 2019 and 2018, we granted 20,455 and 209,700 stock options, respectively, and these options had a weighted average grant-date fair value of $25.51 per share and $68.88 per share, respectively. During the three months ended March 31, 2019 and 2018, we granted 132,820 and 10,000 RSUs, respectively.     

As a result of stock issuances under our equity compensation plans, during the three months ended March 31, 2019 and 2018, we issued 698,000 and 2,854,816 shares of our common stock, respectively.