Stock-Based Compensation

9 Months Ended

Sep. 30, 2018

Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]

Stock-Based Compensation

Note 7 — Stock-Based Compensation

Total stock-based compensation expense was recognized in our Condensed Consolidated Statements of Operations as follows (in thousands):

	Three months ended September 30,				Nine months ended September 30,
	2018		2017		2018		2017
Cost of goods sold	$	1,176	$	547	$	3,470	$	1,639
Research and development		15,365		5,212		40,449		14,429
General and administrative		6,746		3,076		19,976		9,050
Total stock-based compensation	$	23,287	$	8,835	$	63,895	$	25,118

During the three months ended September 30, 2018 and 2017, we granted 190,000 and 833,290 stock options, respectively, and these options had a weighted average grant-date fair value of $30.52 per share and $10.38 per share, respectively. During the nine months ended September 30, 2018 and 2017, we granted 928,675 and 2,118,310 stock options, respectively, and these options had a weighted average grant-date fair value of $39.28 per share and $9.36 per share, respectively. During the three and nine months ended September 30, 2018, we granted 152,151 and 558,391 RSUs, respectively. During the three and nine months ended September 30, 2017, we granted 110,500 RSUs.

As a result of stock issuances under our equity compensation plans, during the three months ended September 30, 2018 and 2017, we issued 642,024 and 1,092,371 shares of our common stock, respectively, and during the nine months ended September 30, 2018 and 2017, we issued 5,247,748 and 3,741,140 shares of our common stock, respectively.