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License and Collaboration Agreements - Additional Information (Detail) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
Feb. 13, 2018
Aug. 23, 2017
Apr. 30, 2018
Nov. 30, 2017
Sep. 30, 2017
Sep. 30, 2016
Mar. 31, 2016
Jun. 30, 2018
Jun. 30, 2017
Dec. 31, 2010
Jun. 30, 2018
Jun. 30, 2017
Dec. 31, 2015
Dec. 31, 2017
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Revenue recognized in period related to performance in prior periods               $ 17,600,000     $ 45,600,000      
Deferred revenue, current portion               17,988,000     17,988,000     $ 18,949,000
Deferred revenue, less current portion               13,780,000     13,780,000     19,021,000
Potential future additional development and regulatory milestones               1,700,000,000     1,700,000,000      
Accounts receivable, net               35,315,000     35,315,000     5,014,000
Revenue related to license activities               1,087,717,000 $ 34,589,000   1,125,735,000 $ 59,317,000    
Deferred revenue               31,768,000     $ 31,768,000     $ 37,970,000
AstraZeneca-Kirin [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Percentage of upfront payment, market access milestone payments, royalties and sales milestone payments             40.00%              
Nektar's [Member] | NKTR-358 [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Received upfront and milestone payment         $ 150,000,000                  
Percentage of sharing in Phase 2 development costs   25.00%                        
Regulatory milestones payment, description                     A portion of the development milestones may be reduced by 50% under certain conditions, related to the final formulation of the approved product and the timing of prior approval (if any) of competitive products with a similar mechanism of action, which could reduce these milestone payments by 75% if both conditions occur.      
Deferred revenue               14,500,000     $ 14,500,000      
NKTR-214 [Member] | Nektar's [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Upfront and milestone payments received from license agreements     $ 1,000,000,000                      
NKTR-214 [Member] | Nektar's [Member] | Maximum [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Maximum total additional cash payments receivable upon achievement of certain development and regulatory milestones               1,400,000,000            
Eligible additional cash payments receivable upon achievement of certain sales milestones               350,000,000            
NKTR-214 [Member] | Nektar's [Member] | BMS Collaboration Agreement [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Global commercialization profits and losses sharing percentage 65.00%                          
NKTR-214 [Member] | Nektar's [Member] | BMS Collaboration Agreement [Member] | Opdivo [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Percentage of sharing development costs 32.50%                          
NKTR-214 [Member] | Nektar's [Member] | BMS Collaboration Agreement [Member] | Opdivo and Yervoy [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Percentage of sharing development costs 22.00%                          
Baxalta Incorporated/Shire [Member] | Hemophilia                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Received under right to sublicense agreement       $ 12,000,000                    
Baxalta Incorporated/Shire [Member] | Hemophilia | European Union [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Upfront and milestone payments received from license agreements                     10,000,000      
Baxalta Incorporated/Shire [Member] | Hemophilia | ASC 606 [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Deferred revenue               1,000,000     1,000,000      
Baxalta Incorporated/Shire [Member] | Hemophilia | ASC 606 [Member] | European Union [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Development milestones received                     10,000,000      
Bristol-Myers Squibb [Member] | Purchase Agreement [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Shares of common stock purchased     8,284,600                      
Sale of stock consideration received     $ 850,000,000                      
Bristol-Myers Squibb [Member] | BMS Collaboration Agreement [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Accounts receivable, net               21,600,000     21,600,000      
Bristol-Myers Squibb [Member] | BMS Collaboration Agreement [Member] | Purchase Agreement [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Total consideration received under agreements     1,850,000,000                      
Estimated fair value of shares     $ 790,200,000                      
Closing date price of common stock     $ 99.36                      
Remaining amount allocated to transaction price     $ 1,059,800,000                      
Potential future development, regulatory and sales milestones               1,800,000,000     1,800,000,000      
Bristol-Myers Squibb [Member] | NKTR-214 [Member] | Research and Development Expense [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Reimbursement of costs               22,500,000     24,800,000      
Bristol-Myers Squibb [Member] | NKTR-214 [Member] | BMS Collaboration Agreement [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Global commercialization profits and losses sharing percentage 35.00%                          
Amount recognized for granting licenses               1,059,800,000     1,059,800,000      
Bristol-Myers Squibb [Member] | NKTR-214 [Member] | BMS Collaboration Agreement [Member] | Research and Development Expense [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Reimbursement of costs               900,000     900,000      
Bristol-Myers Squibb [Member] | NKTR-214 [Member] | BMS Collaboration Agreement [Member] | Opdivo [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Percentage of sharing development costs 67.50%                          
Bristol-Myers Squibb [Member] | NKTR-214 [Member] | BMS Collaboration Agreement [Member] | Opdivo and Yervoy [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Percentage of sharing development costs 78.00%                          
Bristol-Myers Squibb [Member] | NKTR-214 [Member] | Clinical Trial Agreement [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Percentage of out-of-pocket costs to be reimbursed by partner           50.00%                
Eli Lilly and Company [Member] | NKTR-358 [Member] | Phase 1 Clinical Development [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Received upfront and milestone payment         17,600,000                  
Eli Lilly and Company [Member] | NKTR-358 [Member] | Drug Product Development [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Received upfront and milestone payment         6,500,000                  
Eli Lilly and Company [Member] | NKTR-358 [Member] | Maximum [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Potential future additional development and regulatory milestones               250,000,000     250,000,000      
Eli Lilly and Company [Member] | Nektar's [Member] | NKTR-358 [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Percentage of regulatory milestones payments will be reduced under certain conditions   50.00%                        
Percentage of regulatory milestones payments will be reduced if conditions occur   75.00%                        
Eli Lilly and Company [Member] | Nektar's [Member] | NKTR-358 [Member] | Maximum [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Percentage of funding phase 3 development costs on an indication by indication basis borne   25.00%                        
Eli Lilly and Company [Member] | Nektar's [Member] | NKTR-358 [Member] | Minimum [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Percentage of funding phase 3 development costs on an indication by indication basis borne   0.00%                        
Eli Lilly and Company [Member] | License and Maintenance | NKTR-358 [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Received upfront and milestone payment         125,900,000                  
Eli Lilly and Company [Member] | License and Maintenance | NKTR-358 [Member] | ASC 606 [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Revenue related to license activities         $ 125,900,000                  
Eli Lilly [Member] | NKTR-358 [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Percentage of sharing in Phase 2 development costs   75.00%                        
Amgen, Inc. [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Received upfront and milestone payment                   $ 50,000,000        
Amgen, Inc. [Member] | ASC 606 [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Deferred revenue               11,700,000     11,700,000      
AstraZeneca AB [Member] | MOVANTIK and MOVANTIK fixed-dose combination program [Member] | Upfront Payment Arrangement [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Received upfront and milestone payment                         $ 385,000,000  
AstraZeneca AB [Member] | MOVANTIK Fixed-dose Combination Program [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Potential contingent payments based on development events               75,000,000     75,000,000      
AstraZeneca AB [Member] | AstraZeneca-Kirin [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Received upfront and milestone payment                       $ 4,600,000    
Deferred revenue               0     0      
Percentage of upfront payment, market access milestone payments, royalties and sales milestone payments from sublicense agreement retained by our collaboration partner             60.00%              
Other [Member]                            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                            
Potential future additional payments for development and regulatory milestones                     45,500,000      
Deferred revenue               $ 4,600,000     $ 4,600,000