Liability Related to the Sale of Future Royalties - Additional Information (Detail) - USD ($) $ in Thousands |
3 Months Ended | ||
|---|---|---|---|
Feb. 24, 2012 |
Mar. 31, 2017 |
Mar. 31, 2016 |
|
| Liability Related to the Sale of Future Royalties [Line Items] | |||
| Non-cash royalty revenue related to sale of future royalties | $ 6,663 | $ 6,535 | |
| Non-cash interest expense on liability related to sale of future royalties | $ 4,552 | $ 5,045 | |
| Annual interest rate | 17.00% | ||
| Purchase and Sale Agreement with RPI [Member] | |||
| Liability Related to the Sale of Future Royalties [Line Items] | |||
| Proceeds from sale of royalty rights | $ 124,000 | ||
| Transaction costs related to sale of potential future royalties | $ 4,400 | ||