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Stockholders' Equity - Summarization of Common Stock Shares for Issuance Under Existing Equity Compensation Plans (Detail) (USD $)
In Thousands, except Per Share data, unless otherwise specified
Dec. 31, 2014
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Number of Securities to be Issued Upon Exercise of Outstanding Options 21,995nktr_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAndRestrictedStockUnitsOutstanding
Number of Securities Remaining Available for Issuance Under Equity Compensation Plans (Excluding Securities Reflected in Column) 2,812nktr_NumberOfSecuritiesAvailableForIssuanceUnderEquityCompensationPlans
Weighted-Average Exercise Price of Outstanding Options $ 10.50us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageExercisePrice1
Equity Compensation Plans Approved by Security Holders [Member]  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Number of Securities to be Issued Upon Exercise of Outstanding Options 18,601nktr_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAndRestrictedStockUnitsOutstanding
/ us-gaap_AwardTypeAxis
= nktr_EquityCompensationPlansApprovedByShareholdersMember
Number of Securities Remaining Available for Issuance Under Equity Compensation Plans (Excluding Securities Reflected in Column) 2,812nktr_NumberOfSecuritiesAvailableForIssuanceUnderEquityCompensationPlans
/ us-gaap_AwardTypeAxis
= nktr_EquityCompensationPlansApprovedByShareholdersMember
Weighted-Average Exercise Price of Outstanding Options $ 10.68us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageExercisePrice1
/ us-gaap_AwardTypeAxis
= nktr_EquityCompensationPlansApprovedByShareholdersMember
Equity Compensation Plans Not Approved by Security Holders [Member]  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Number of Securities to be Issued Upon Exercise of Outstanding Options 3,394nktr_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAndRestrictedStockUnitsOutstanding
/ us-gaap_AwardTypeAxis
= nktr_EquityCompensationPlansUnapprovedBySecurityHoldersMember
Weighted-Average Exercise Price of Outstanding Options $ 9.52us-gaap_SharebasedCompensationSharesAuthorizedUnderStockOptionPlansExercisePriceRangeExercisableOptionsWeightedAverageExercisePrice1
/ us-gaap_AwardTypeAxis
= nktr_EquityCompensationPlansUnapprovedBySecurityHoldersMember