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Organization and Summary of Significant Accounting Policies - Additional Information (Detail) (USD $)
Share data in Millions, unless otherwise specified
12 Months Ended 1 Months Ended
Dec. 31, 2014
Reporting_Unit
Customer
Dec. 31, 2013
Customer
Dec. 31, 2012
Jul. 31, 2012
Jul. 11, 2012
Organization And Summary Of Significant Accounting Policies [Line Items]          
Cash and investments in marketable securities $ 262,824,000nktr_CashRestrictedCashCashEquivalentsAndAvailableForSaleInvestments $ 262,026,000nktr_CashRestrictedCashCashEquivalentsAndAvailableForSaleInvestments      
Indebtedness 151,800,000nktr_DebtCapitalLeaseAndOtherLongTermLiabilities        
Senior secured notes, issued 125,000,000us-gaap_SeniorLongTermNotes 125,000,000us-gaap_SeniorLongTermNotes      
Restricted cash 25,000,000us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue        
Maximum maturity term of investments in marketable securities to be considered as cash equivalents Three months        
Maturity term of investments considered as short-term Less than one year        
Number of customers accounted for major accounts receivable 3nktr_NumberOfCustomersAccountedForMajorAccountsReceivable 3nktr_NumberOfCustomersAccountedForMajorAccountsReceivable      
Percentage of accounts receivable customers one 40.00%nktr_PercentageOfAccountsReceivableCustomersOne 30.00%nktr_PercentageOfAccountsReceivableCustomersOne      
Percentage of accounts receivable customers two 31.00%nktr_PercentageOfAccountsReceivableCustomersTwo 28.00%nktr_PercentageOfAccountsReceivableCustomersTwo      
Percentage of accounts receivable customers three 15.00%nktr_PercentageOfAccountsReceivableCustomersThree 28.00%nktr_PercentageOfAccountsReceivableCustomersThree      
Number of reporting unit evaluated for goodwill 1nktr_NumberOfReportingUnitsToEvaluateGoodwillForImpairment        
Reduction of prior periods research and development expenses 4,700,000nktr_ResearchAndDevelopmentExpenditureCredits        
Minimum percentage of amount realized upon ultimate settlement 50.00%nktr_PercentageOfAmountRealizedUponUltimateSettlement        
Stock Options [Member]          
Organization And Summary Of Significant Accounting Policies [Line Items]          
Weighted average diluted securities excluded from diluted net loss per share 21.9us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
/ us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis
= us-gaap_StockOptionMember
20.7us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
/ us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis
= us-gaap_StockOptionMember
18.8us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
/ us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis
= us-gaap_StockOptionMember
   
Minimum [Member]          
Organization And Summary Of Significant Accounting Policies [Line Items]          
Property and equipment estimated useful lives 3        
Maximum [Member]          
Organization And Summary Of Significant Accounting Policies [Line Items]          
Property and equipment estimated useful lives 7        
12% Senior Secured Notes Due July 2017 [Member]          
Organization And Summary Of Significant Accounting Policies [Line Items]          
Senior secured notes, issued         125,000,000us-gaap_SeniorLongTermNotes
/ us-gaap_LongtermDebtTypeAxis
= us-gaap_SeniorNotesMember
Senior secured notes, interest rate 12.00%us-gaap_DebtInstrumentInterestRateStatedPercentage
/ us-gaap_LongtermDebtTypeAxis
= us-gaap_SeniorNotesMember
      12.00%us-gaap_DebtInstrumentInterestRateStatedPercentage
/ us-gaap_LongtermDebtTypeAxis
= us-gaap_SeniorNotesMember
Senior secured notes, maturity date Jul. 15, 2017     Jul. 15, 2017  
Restricted cash $ 25,000,000us-gaap_RestrictedCashAndCashEquivalentsAtCarryingValue
/ us-gaap_LongtermDebtTypeAxis
= us-gaap_SeniorNotesMember