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License and Collaboration Agreements - License, Collaboration and Other Revenue (Detail) (USD $)
In Thousands, unless otherwise specified
3 Months Ended 9 Months Ended
Sep. 30, 2014
Sep. 30, 2013
Sep. 30, 2014
Sep. 30, 2013
License And Collaboration Agreements [Line Items]        
License, collaboration and other revenue $ 120,556 $ 41,360 $ 146,422 $ 67,195
AstraZeneca AB [Member] | MOVANTIKTM (NKTR-118) and MOVANTIKTM fixed-dose combination program (NKTR-119) [Member]
       
License And Collaboration Agreements [Line Items]        
License, collaboration and other revenue 105,000 25,000 105,001 25,016
Baxter Healthcare [Member] | BAX 855 (Hemophilia) [Member]
       
License And Collaboration Agreements [Line Items]        
License, collaboration and other revenue 9,096 201 10,103 1,499
Roche [Member] | PEGASYS and MIRCERA [Member]
       
License And Collaboration Agreements [Line Items]        
License, collaboration and other revenue 3,200 2,625 9,614 7,875
Bayer Healthcare LLC [Member] | BAY41-6551 (Amikacin Inhale) [Member]
       
License And Collaboration Agreements [Line Items]        
License, collaboration and other revenue 793 779 3,939 14,604
Amgen, Inc. [Member] | Neulasta [Member]
       
License And Collaboration Agreements [Line Items]        
License, collaboration and other revenue 1,250 1,250 3,750 3,750
Other [Member]
       
License And Collaboration Agreements [Line Items]        
License, collaboration and other revenue $ 1,217 $ 11,505 $ 14,015 $ 14,451