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Liability Related to Sale of Future Royalties - Additional Information (Detail) (USD $)
3 Months Ended 9 Months Ended 1 Months Ended 0 Months Ended
Sep. 30, 2014
Sep. 30, 2013
Sep. 30, 2014
Sep. 30, 2013
Mar. 31, 2013
Milestone Scenario One [Member]
Mar. 31, 2014
Milestone Scenario Two [Member]
Feb. 24, 2012
Purchase and Sale Agreement with RPI [Member]
Liability Related to Sale of Future Royalties [Line Items]              
Proceeds from sale of royalty rights             $ 124,000,000
Non-cash royalty revenue 6,143,000 4,523,000 16,753,000 12,744,000      
Annual interest rate     17.00%        
Payment made for milestone not achieved year one         3,000,000    
Payment made for milestone not achieved year two           $ 7,000,000  
Royalty agreement contingent payment description     As a result of worldwide net sales of MIRCERAfor the 12 month periods ended on December 31, 2013 and 2012 not reaching certain minimum thresholds.