Liability Related to Sale of Future Royalties - Additional Information (Detail) (USD $)	12 Months Ended			1 Months Ended	12 Months Ended	1 Months Ended	12 Months Ended	1 Months Ended		12 Months Ended
	Dec. 31, 2013	Dec. 31, 2012	Dec. 31, 2013 Maximum [Member]	Mar. 31, 2013 Milestone Scenario One [Member]	Dec. 31, 2013 Milestone Scenario One [Member]	Dec. 31, 2013 Milestone Scenario Two [Member]	Dec. 31, 2013 Milestone Scenario Two [Member]	Feb. 24, 2012 Purchase and Sale Agreement with RPI [Member]	Dec. 31, 2013 MIRCERA [Member]	Dec. 31, 2013 CIMZIA and MIRCERA [Member]	Dec. 31, 2012 CIMZIA and MIRCERA [Member]
Liability Related to Sale of Future Royalties [Line Items]
Proceeds from sale of royalty rights								$ 124,000,000
Transaction costs related to sale of potential future royalties								4,400,000
Increase in non-cash royalty revenue in 2013 based on estimates of net sales	4,600,000
Non-cash royalties from net sales										22,100,000	10,800,000
Annual interest rate	17.00%
Payment made for milestone not achieved year one				3,000,000
Potential payments milestone not achieved year two						7,000,000
Royalty agreement contingent payment description					Because worldwide net sales of MIRCERAfor the 12 month period ended December 31, 2012 did not reach a required threshold.		If the specified worldwide net sales threshold of MIRCERAfor the 12 month period ended December 31, 2013 is not achieved.
Contingent payment related to royalty obligation			7,000,000
Other current liabilities	$ 14,123,000	$ 9,414,000							$ 7,000,000