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License and Collaboration Agreements (Details Textual) (USD $)
In Millions, unless otherwise specified
1 Months Ended 3 Months Ended 3 Months Ended 12 Months Ended 3 Months Ended 1 Months Ended 3 Months Ended
Mar. 31, 2012
Dec. 31, 2009
Hoffmann-La Roche [Member]
License Option [Member]
Dec. 31, 2010
Amgen Inc [Member]
Mar. 31, 2012
Amgen Inc [Member]
Mar. 31, 2012
AstraZeneca AB [Member]
Mar. 31, 2012
Bayer Healthcare LLC [Member]
Dec. 31, 2007
Bayer Healthcare LLC [Member]
Up-front Payment Arrangement [Member]
Dec. 31, 2007
Bayer Healthcare LLC [Member]
Performance milestone payments [Member]
Dec. 31, 2005
Baxter Healthcare [Member]
Mar. 31, 2012
Baxter Healthcare [Member]
Dec. 31, 2009
NKTR-118 and NKTR-119 [Member]
AstraZeneca AB [Member]
Up-front Payment Arrangement [Member]
Mar. 31, 2012
MIRCERA [Member]
Hoffmann-La Roche [Member]
Feb. 29, 2012
MIRCERA [Member]
Hoffmann-La Roche [Member]
Up-front Payment Arrangement [Member]
Mar. 31, 2012
MIRCERA [Member]
Hoffmann-La Roche [Member]
Up-front Payment Arrangement [Member]
Mar. 31, 2012
MIRCERA [Member]
Hoffmann-La Roche [Member]
Performance milestone payments [Member]
Feb. 29, 2012
MIRCERA [Member]
Hoffmann-La Roche [Member]
Performance milestone payments [Member]
Mar. 31, 2012
NKTR-118 [Member]
Mar. 31, 2012
NKTR-118 [Member]
AstraZeneca AB [Member]
Mar. 31, 2012
NKTR-119 [Member]
AstraZeneca AB [Member]
Mar. 31, 2012
Hemophilia [Member]
Baxter Healthcare [Member]
Mar. 31, 2012
Hemophilia B [Member]
Baxter Healthcare [Member]
Mar. 31, 2012
OMONTYS [Member]
Affymax Inc [Member]
Mar. 27, 2012
OMONTYS [Member]
Affymax Inc [Member]
Mar. 31, 2012
PEGASYS [Member]
Hoffmann-La Roche [Member]
License and Collaboration Agreements (Textual) [Abstract]                                                
Potential future payments for development milestones $ 172.1         $ 60.0                   $ 22.0       $ 28.0 $ 11.0      
Substantive milestone revenue                                             2.0  
Deferred Revenue       42.9   26.7       5.5   7.9                   7.7   19.2
Received upfront and milestone payments   31.0 50.0       40.0 20.0 9.0   125.0   5.0 5.0 3.0                  
Revenue recognized as contractual obligations completed                       0.1                        
Contingent payments receivable based on development events to be pursued and completed solely by others         95.0                       140.0 235.0 75.0          
Performance milestone to be used to reimburse future clinical trial costs           10.0                                    
Expected sales consideration                       $ 27.0