CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2024	Mar. 31, 2023
Revenue:
Total revenue	$ 21,639	$ 21,594
Operating costs and expenses:
Cost of goods sold	8,534	7,060
Research and development	27,408	30,469
General and administrative	20,149	21,081
Restructuring, impairment and costs of terminated program	975	21,193
Impairment of goodwill	0	76,501
Total operating costs and expenses	57,066	156,304
Loss from operations	(35,427)	(134,710)
Non-operating income (expense):
Non-cash interest expense on liabilities related to the sales of future royalties	(5,531)	(6,405)
Interest income	4,220	4,335
Other income (expense), net	(99)	(301)
Total non-operating income (expense), net	(1,410)	(2,371)
Loss before provision for income taxes	(36,837)	(137,081)
Benefit for income taxes	(35)	(63)
Net loss	$ (36,802)	$ (137,018)
Basic net loss per share (in dollars per share)	$ (0.19)	$ (0.73)
Diluted net loss per share (in dollars per share)	$ (0.19)	$ (0.73)
Weighted average shares outstanding used in computing basic net loss per share (in shares)	194,746	188,875
Weighted average shares outstanding used in computing diluted net loss per share (in shares)	194,746	188,875
Product sales
Revenue:
Total revenue	$ 6,034	$ 4,718
Non-cash royalty revenue related to the sales of future royalties
Revenue:
Total revenue	15,508	16,861
License, collaboration and other revenue
Revenue:
Total revenue	$ 97	$ 15