Organization and Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($)			1 Months Ended			3 Months Ended
	Mar. 04, 2024	Feb. 12, 2024	Mar. 31, 2024	Jun. 30, 2023	Apr. 30, 2022	Mar. 31, 2024	Mar. 31, 2023	Dec. 31, 2023
Organization And Summary Of Significant Accounting Policies [Line Items]
Cash and investments in marketable securities			$ 326,016,000			$ 326,016,000		$ 329,441,000
Proceeds from issuance of pre-funded warrant						30,000,000	$ 0
Accounts receivable, credit loss expense (reversal)						$ 0	$ 0
Bristol Myers Squibb Company
Organization And Summary Of Significant Accounting Policies [Line Items]
Sale of stock repurchased cash consideration		$ 3,000,000
Sale of stock shares repurchased		8,300,000
Securities Purchase Agreement | TCG Crossover Fund II, L.P.
Organization And Summary Of Significant Accounting Policies [Line Items]
Proceeds from issuance of pre-funded warrant	$ 30,000,000		$ 30,000,000
2020 Purchase and Sale Agreement
Organization And Summary Of Significant Accounting Policies [Line Items]
Amount exchanged to remove cap on royalties	$ 15,000,000
Pre-Funded Warrant | Securities Purchase Agreement | TCG Crossover Fund II, L.P.
Organization And Summary Of Significant Accounting Policies [Line Items]
Number of warrants issued to be purchase common shares	25,000,000		25,000,000			25,000,000
Shares issued, price per share	$ 1.2		$ 1.2			$ 1.2
Employee Severance | 2022 Restructuring Plan
Organization And Summary Of Significant Accounting Policies [Line Items]
Workforce termination, percentage					70.00%
Employee Severance | 2023 Restructuring Plan
Organization And Summary Of Significant Accounting Policies [Line Items]
Workforce termination, percentage				60.00%