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Stock-Based Compensation (Tables)
6 Months Ended
Jun. 30, 2011
Stock-Based Compensation (Tables) [Abstract]  
Total stock-based compensation expense
                                 
    Three months ended     Six months ended  
    June 30,     June 30,  
    2011     2010     2011     2010  
Cost of goods sold
  $ 330     $ 229     $ 662     $ 435  
Research and development expense
    2,120       1,734       4,089       3,301  
General and administrative expense
    2,430       2,398       4,931       4,369  
 
                       
Total stock-based compensation
  $ 4,880     $ 4,361     $ 9,682     $ 8,105