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License and Collaboration Agreements (Tables)
6 Months Ended
Jun. 30, 2011
License and Collaboration Agreements (Tables) [Abstract]  
License, collaboration, and other revenue
                                     
        Three months ended     Six months ended  
        June 30,     June 30,  
Partner   Drug or Drug Candidate   2011     2010     2011     2010  
F. Hoffmann- LaRoche
  PEGASYS®   $ 1,283     $ 1,283     $ 2,566     $ 2,566  
Amgen, Inc.
  Neulasta®     1,250             2,500        
Bayer Healthcare LLC
  BAY41-6551 (Amikacin Inhale)     750       818       1,500       1,705  
AstraZeneca AB
  NKTR-118 and NKTR-119     845       27,579       1,086       53,306  
Other
        2,195       1,729       5,177       3,485  
 
                           
 
                                   
License, collaboration, and other revenue
      $ 6,323     $ 31,409     $ 12,829     $ 61,062