CONDENSED CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022
Current assets:
Cash and cash equivalents	$ 76,955	$ 88,227
Short-term investments	379,872	416,750
Accounts receivable	2,995	5,981
Inventory, net	20,235	19,202
Other current assets	11,009	15,808
Total current assets	491,066	545,968
Property, plant and equipment, net	27,084	32,451
Operating lease right-of-use assets	42,187	53,435
Goodwill	0	76,501
Other assets	1,406	2,245
Total assets	561,743	710,600
Current liabilities:
Accounts payable	3,696	12,980
Accrued expenses	37,410	36,557
Operating lease liabilities, current portion	18,773	18,667
Total current liabilities	59,879	68,204
Operating lease liabilities, less current portion	109,389	112,829
Liabilities related to the sales of future royalties, net	145,131	155,378
Other long-term liabilities	6,479	7,551
Total liabilities	320,878	343,962
Commitments and contingencies
Stockholders’ equity:
Preferred stock, $0.0001 par value; 10,000 shares authorized; no shares designated or outstanding at March 31, 2023 or December 31, 2022, respectively	0	0
Common stock, $0.0001 par value; 300,000 shares authorized; 189,235 shares and 188,560 shares outstanding at March 31, 2023 and December 31, 2022, respectively	19	19
Capital in excess of par value	3,584,738	3,574,719
Accumulated other comprehensive loss	(5,681)	(6,907)
Accumulated deficit	(3,338,211)	(3,201,193)
Total stockholders’ equity	240,865	366,638
Total liabilities and stockholders’ equity	$ 561,743	$ 710,600