Restructuring, Impairment and Other Costs of Terminated Program - Sublease Information (Details) - USD ($) $ in Thousands	3 Months Ended	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2022	Jun. 30, 2021
Restructuring Cost and Reserve [Line Items]
Impairment expense for facilities		$ 52,201
Impairment of other property, plant and equipment		5,120
Impairment of right-of-use assets and property, plant and equipment	$ 57,321	57,321	$ 0
Reported Value Measurement
Restructuring Cost and Reserve [Line Items]
Property, plant and equipment and Operating lease right-of-use assets	87,268	87,268
Property, Plant and Equipment
Restructuring Cost and Reserve [Line Items]
Impairment expense for facilities		9,372
Impairment of other property, plant and equipment		5,120
Impairment of right-of-use assets and property, plant and equipment		14,492
Property, Plant and Equipment | Reported Value Measurement
Restructuring Cost and Reserve [Line Items]
Property, plant and equipment and Operating lease right-of-use assets	16,348	16,348
Operating Lease Right-of-Use Assets
Restructuring Cost and Reserve [Line Items]
Impairment expense for facilities		42,829
Impairment of right-of-use assets and property, plant and equipment		42,829
Operating Lease Right-of-Use Assets | Reported Value Measurement
Restructuring Cost and Reserve [Line Items]
Property, plant and equipment and Operating lease right-of-use assets	70,920	70,920
Fair Value, Level 3 | Estimate of Fair Value Measurement
Restructuring Cost and Reserve [Line Items]
Property, plant and equipment and Operating lease right-of-use assets	35,067	35,067
Fair Value, Level 3 | Property, Plant and Equipment | Estimate of Fair Value Measurement
Restructuring Cost and Reserve [Line Items]
Property, plant and equipment and Operating lease right-of-use assets	6,976	6,976
Fair Value, Level 3 | Operating Lease Right-of-Use Assets | Estimate of Fair Value Measurement
Restructuring Cost and Reserve [Line Items]
Property, plant and equipment and Operating lease right-of-use assets	$ 28,091	$ 28,091