Stock-Based Compensation (Tables)

6 Months Ended

Jun. 30, 2022

Share-Based Payment Arrangement [Abstract]

Schedule of Stock-Based Compensation Expense

We recognized total stock-based compensation expense in our Condensed Consolidated Statements of Operations as follows (in thousands):

	Three Months Ended June 30,				Six months ended June 30,
	2022		2021		2022		2021
Cost of goods sold	$	649	$	716	$	1,317	$	1,443
Research and development	4,751		13,479		16,793		$	27,641
General and administrative	4,781		9,519		13,032		$	18,528
Restructuring, impairment and other costs of terminated program	922		$	—	922		$	—
Total stock-based compensation	$	11,103	$	23,714	$	32,064	$	47,612

Schedule of Share-based Compensation, Activity

We issued stock-based awards of our common stock as follows (shares in thousands):

	Three Months Ended June 30,				Six Months Ended June 30,
	2022		2021		2022		2021
Options granted	85		$	157	107		$	278
Weighted-average grant-date fair value of options granted	$	2.47	$	9.78	$	3.33	$	10.23
RSUs granted	626		520		1,031		887
Weighted-average grant-date fair value of RSUs granted	$	3.97	$	18.20	$	6.10	$	19.21
Shares issued under equity compensation plans	1,131		1,483		1,937		3,682