Stock-Based Compensation (Tables)

3 Months Ended

Mar. 31, 2021

Share-based Payment Arrangement [Abstract]

Stock-Based Compensation Expense

We recognized total stock-based compensation expense in our Condensed Consolidated Statements of Operations as follows (in thousands):

	Three months ended March 31,
	2021		2020
Cost of goods sold	$	727	$	761
Research and development	14,162		15,453
General and administrative	9,009		7,997
Impairment of assets and other costs for terminated program	—		1,025
Total stock-based compensation	$	23,898	$	25,236

Share-based Compensation, Activity

We issued stock-based awards and resulting shares of our common stock as follows (shares in thousands):

	Three months ended March 31,
	2021		2020
Options granted	121		49
Weighted-average grant-date fair value of options granted	$	10.82	$	11.88
RSUs granted	367		245
Weighted-average grant-date fair value of RSUs granted	$	20.63	$	18.91
Shares issued under equity compensation plans	2,199		1,358