Stock-Based Compensation (Tables)

6 Months Ended

Jun. 30, 2020

Share-based Payment Arrangement [Abstract]

Stock-Based Compensation Expense

We recognized total stock-based compensation expense in our Condensed Consolidated Statements of Operations as follows (in thousands):

	Three months ended June 30,				Six months ended June 30,
	2020		2019		2020		2019
Cost of goods sold	$	664	$	1,086	$	1,424	$	2,089
Research and development	14,161		15,430		29,614		31,870
General and administrative	8,546		8,006		16,544		15,948
Impairment of assets and other costs for terminated program	—		—		1,025		—
Total stock-based compensation	$	23,371	$	24,522	$	48,607	$	49,907

Share-based Compensation, Activity

We issued stock-based awards and resulting shares of our common stock as follows (shares in thousands):

	Three months ended June 30,				Six months ended June 30,
	2020		2019		2020		2019
Options granted	—		95		49		115
Weighted-average grant-date fair value of options granted	$	—	$	17.00	$	11.88	$	18.51
RSUs granted	275		263		520		396
Weighted-average grant-date fair value of RSUs granted	$	21.65	$	31.76	$	20.36	$	34.85
Shares issued under equity compensation plans	947		738		2,305		1,436