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License and Collaboration Agreements - Additional Information (Detail) - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended 76 Months Ended
Feb. 13, 2018
Aug. 23, 2017
Dec. 31, 2018
Apr. 30, 2018
Jan. 31, 2018
Nov. 30, 2017
Sep. 30, 2017
Aug. 31, 2017
Sep. 30, 2016
Mar. 31, 2016
Sep. 30, 2019
Sep. 30, 2018
Dec. 31, 2010
Sep. 30, 2019
Sep. 30, 2018
Dec. 31, 2015
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Revenue recognized in period related to performance in prior periods                     $ 20,500,000 $ 18,600,000   $ 56,600,000 $ 64,200,000  
Deferred revenue, current portion     $ 13,892,000               8,392,000     8,392,000    
Deferred revenue, less current portion     10,744,000               6,779,000     6,779,000    
Potential future additional development and regulatory milestones                     1,700,000,000     1,700,000,000    
Accounts receivable     43,213,000               41,205,000     41,205,000    
Revenue recognized from contracts with customers                     29,218,000 27,762,000   80,755,000 1,153,497,000  
Deferred revenue     24,636,000               15,171,000     15,171,000    
NKTR-358 | Nektar's                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Deferred revenue                     3,100,000     3,100,000    
BMS Collaboration Agreement | NKTR-214 | Nektar's                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Upfront and milestone payments received from license agreements       $ 1,000,000,000.0                        
Global commercialization profits and losses sharing percentage 65.00%                              
Percentage of sharing production costs 65.00%                              
Maximum total additional cash payments receivable upon achievement of certain development and regulatory milestones       1,400,000,000                        
BMS Collaboration Agreement | NKTR-214 | Nektar's | Maximum                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Eligible additional cash payments receivable upon achievement of certain sales milestones       $ 350,000,000.0                        
BMS Collaboration Agreement | NKTR-214 | Nektar's | Opdivo                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Percentage of sharing development costs 32.50%                              
BMS Collaboration Agreement | NKTR-214 | Nektar's | Opdivo and Yervoy                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Percentage of sharing development costs 22.00%                              
NKTR-358 | Nektar's                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Received upfront and milestone payment             $ 150,000,000.0                  
Percentage of sharing in Phase 2 development costs   25.00%                            
Nektar                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Percentage of upfront payment, market access milestones, royalties and sales milestones                   40.00%            
Baxalta Incorporated/Takeda | Hemophilia                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Received under right to sublicense agreement           $ 12,000,000.0                    
Baxalta Incorporated/Takeda | Hemophilia | Annual Sales Level Milestone                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Revenue recognized from contracts with customers     $ 10,000,000.0                          
Baxalta Incorporated/Takeda | Hemophilia | European Union                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Upfront and milestone payments received from license agreements                             10,000,000.0  
Revenue recognized from contracts with customers         $ 10,000,000.0                   10,000,000.0  
Bristol-Myers Squibb Company | Purchase Agreement                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Shares issued (in shares)       8,284,600                        
Sale of stock consideration received       $ 850,000,000.0                        
Bristol-Myers Squibb Company | NKTR-214 | Research and Development Expense                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Reimbursement of expenses                     28,300,000 $ 18,900,000   81,400,000 42,800,000  
Bristol-Myers Squibb Company | BMS Collaboration Agreement                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Accounts receivable                     27,700,000     27,700,000    
Bristol-Myers Squibb Company | BMS Collaboration Agreement | Purchase Agreement                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Total consideration received under agreements       1,850,000,000                        
Estimated fair value of shares       $ 790,200,000                        
Closing date price of common stock (in dollars per share)       $ 99.36                        
Remaining amount allocated to transaction price       $ 1,059,800,000                        
Potential future development, regulatory and sales milestones       $ 1,800,000,000                        
Bristol-Myers Squibb Company | BMS Collaboration Agreement | NKTR-214                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Global commercialization profits and losses sharing percentage 35.00%                              
Percentage of sharing production costs 35.00%                              
Amount recognized for granting licenses                             $ 1,059,800,000  
Bristol-Myers Squibb Company | BMS Collaboration Agreement | NKTR-214 | Opdivo                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Percentage of sharing development costs 67.50%                              
Bristol-Myers Squibb Company | BMS Collaboration Agreement | NKTR-214 | Opdivo and Yervoy                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Percentage of sharing development costs 78.00%                              
Bristol-Myers Squibb Company | Clinical Trial Agreement | NKTR-214                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Percentage of out-of-pocket costs to be reimbursed by partner                 50.00%              
Eli Lilly and Company | NKTR-358 | ASC 606                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Revenue recognized from contracts with customers               $ 125,900,000                
Eli Lilly and Company | NKTR-358 License                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Amount of transaction price allocated to performance obligation             125,900,000                  
Eli Lilly and Company | NKTR-358 | Maximum                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Potential future additional development and regulatory milestones   $ 250,000,000.0                            
Eli Lilly and Company | NKTR-358 | Nektar's                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Percentage of regulatory milestones payments will be reduced under certain conditions   50.00%                            
Percentage of regulatory milestones payments will be reduced if conditions occur   75.00%                            
Eli Lilly and Company | NKTR-358 | Nektar's | Maximum                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Percentage of funding phase 3 development costs on an indication by indication basis borne   25.00%                            
Eli Lilly and Company | NKTR-358 | Nektar's | Minimum                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Percentage of funding phase 3 development costs on an indication by indication basis borne   0.00%                            
Eli Lilly and Company | Phase 1 Clinical Development | NKTR-358 License                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Amount of transaction price allocated to performance obligation             17,600,000                  
Eli Lilly and Company | Drug Product Development | NKTR-358 License                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Amount of transaction price allocated to performance obligation             $ 6,500,000                  
Eli Lilly | NKTR-358                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Percentage of sharing in Phase 2 development costs   75.00%                            
Amgen, Inc.                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Received upfront and milestone payment                         $ 50,000,000.0      
Amgen, Inc. | ASC 606                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Deferred revenue                     5,400,000     $ 5,400,000    
AstraZeneca AB | MOVANTIK and MOVENTIG                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Received upfront and milestone payment                               $ 385,000,000.0
Amount of post approval study expenses eligible for reimbursement                           33.00%    
Amount of post approval study expenses eligible for reimbursement, maximum                           $ 35,000,000.0    
Share of expenses                           1,700,000    
AstraZeneca AB | AstraZeneca-Kirin                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Deferred revenue                     0     0    
Percentage of upfront payment, market access milestone payments, royalties and sales milestone payments from sublicense agreement retained by our collaboration partner                   60.00%            
Baxalta Inc. / Takeda Pharmaceutical Company Ltd. and other                                
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                                
Deferred revenue                     6,000,000.0     6,000,000.0    
Potential future additional payments for development milestones                     $ 45,500,000     $ 45,500,000