-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 NMYcauTWemnmmRswOcwLmiVRUaCdXdIHho9ThSFIiCA0J63GRTTDkiPOvZkPr7Rl
 JOqtE+sk0S1OrokDVVyJ9A==

<SEC-DOCUMENT>0000921895-08-002504.txt : 20081003
<SEC-HEADER>0000921895-08-002504.hdr.sgml : 20081003
<ACCEPTANCE-DATETIME>20081003173932
ACCESSION NUMBER:		0000921895-08-002504
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20081001
FILED AS OF DATE:		20081003
DATE AS OF CHANGE:		20081003

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			ACCIPITER LIFE SCIENCES FUND LP
		CENTRAL INDEX KEY:			0001211729

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-22056
		FILM NUMBER:		081107691

	BUSINESS ADDRESS:	
		STREET 1:		153 EAST 53RD STREET 55TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		2125215059

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			ACCIPITER LIFE SCIENCES FUND OFFSHORE LTD
		CENTRAL INDEX KEY:			0001214706

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-22056
		FILM NUMBER:		081107690

	BUSINESS ADDRESS:	
		STREET 1:		P O BOX 1234
		STREET 2:		GEORGE TOWN
		CITY:			GRAND CAYMAN CA IS BRI WE IND
		STATE:			E9
		ZIP:			00000
		BUSINESS PHONE:		441-292-8900

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			HOFFMAN GABE
		CENTRAL INDEX KEY:			0001322420

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-22056
		FILM NUMBER:		081107696

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		212-705-8700

	MAIL ADDRESS:	
		STREET 1:		C/O ACCIPITER CAPITAL MANAGEMENT, LLC
		STREET 2:		399 PARK AVENUE, 37TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			RURAL/METRO CORP /DE/
		CENTRAL INDEX KEY:			0000906326
		STANDARD INDUSTRIAL CLASSIFICATION:	LOCAL & SUBURBAN TRANSIT & INTERURBAN HWY PASSENGER TRAINS [4100]
		IRS NUMBER:				860746929
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0630

	BUSINESS ADDRESS:	
		STREET 1:		9221 EAST VIA DE VENTURA
		CITY:			SCOTTSDALE
		STATE:			AZ
		ZIP:			85258
		BUSINESS PHONE:		4806063886

	MAIL ADDRESS:	
		STREET 1:		9221 EAST VIA DE VENTURA
		CITY:			SCOTTSDALE
		STATE:			AZ
		ZIP:			85258

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	RURAL METRO CORP /DE/
		DATE OF NAME CHANGE:	19930528

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			ACCIPITER CAPITAL MANAGEMENT, LLC
		CENTRAL INDEX KEY:			0001280190
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-22056
		FILM NUMBER:		081107695

	BUSINESS ADDRESS:	
		STREET 1:		399 PARK AVENUE
		STREET 2:		38TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		2127058700

	MAIL ADDRESS:	
		STREET 1:		399 PARK AVENUE
		STREET 2:		38TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022

	FORMER NAME:	
		FORMER CONFORMED NAME:	ACCIPITER CAPITAL MANAGEMENT
		DATE OF NAME CHANGE:	20040213

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Accipiter Life Sciences Fund II Offshore Ltd
		CENTRAL INDEX KEY:			0001351046

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-22056
		FILM NUMBER:		081107693

	BUSINESS ADDRESS:	
		STREET 1:		399 PARK AVE 38TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		212-705-8700

	MAIL ADDRESS:	
		STREET 1:		399 PARK AVE 38TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			ACCIPITER LIFE SCIENCES FUND II QP L P
		CENTRAL INDEX KEY:			0001351186

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-22056
		FILM NUMBER:		081107692

	BUSINESS ADDRESS:	
		STREET 1:		399 PARK AVE 37TH FL
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		212-705-8700

	MAIL ADDRESS:	
		STREET 1:		399 PARK AVE 37TH FL
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			ACCIPITER LIFE SCIENCES FUND II L P
		CENTRAL INDEX KEY:			0001351187

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-22056
		FILM NUMBER:		081107694

	BUSINESS ADDRESS:	
		STREET 1:		399 PARK AVE 37TH FL
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		212-705-8700

	MAIL ADDRESS:	
		STREET 1:		399 PARK AVE 37TH FL
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Candens Capital LLC
		CENTRAL INDEX KEY:			0001351609
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-22056
		FILM NUMBER:		081107689

	BUSINESS ADDRESS:	
		STREET 1:		C/O ACCIPITER CAPITAL MANAGEMENT, LLC
		STREET 2:		399 PARK AVENUE, 38TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		212-705-8720

	MAIL ADDRESS:	
		STREET 1:		C/O ACCIPITER CAPITAL MANAGEMENT, LLC
		STREET 2:		399 PARK AVENUE, 38TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>acc20.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2008-10-01</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000906326</issuerCik>
        <issuerName>RURAL/METRO CORP /DE/</issuerName>
        <issuerTradingSymbol>(RURL)</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001280190</rptOwnerCik>
            <rptOwnerName>ACCIPITER CAPITAL MANAGEMENT, LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>666 5TH AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2>35TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10103</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001351187</rptOwnerCik>
            <rptOwnerName>ACCIPITER LIFE SCIENCES FUND II L P</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>666 5TH AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2>35TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10103</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001351046</rptOwnerCik>
            <rptOwnerName>Accipiter Life Sciences Fund II Offshore Ltd</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>666 5TH AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2>35TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10103</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001351186</rptOwnerCik>
            <rptOwnerName>ACCIPITER LIFE SCIENCES FUND II QP L P</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>666 5TH AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2>35TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10103</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001211729</rptOwnerCik>
            <rptOwnerName>ACCIPITER LIFE SCIENCES FUND LP</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>666 5TH AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2>35TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10103</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001214706</rptOwnerCik>
            <rptOwnerName>ACCIPITER LIFE SCIENCES FUND OFFSHORE LTD</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>666 5TH AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2>35TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10103</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001351609</rptOwnerCik>
            <rptOwnerName>Candens Capital LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>666 5TH AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2>35TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10103</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001322420</rptOwnerCik>
            <rptOwnerName>HOFFMAN GABE</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>666 5TH AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2>35TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10103</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2008-10-01</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>J</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>409904</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>2.5400</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1173112</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By ALSF (Offshore), Ltd.</value>
                    <footnoteId id="F2"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2008-10-01</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>J</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>416284</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>2.5400</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>643049</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By ALSF II (Offshore), Ltd.</value>
                    <footnoteId id="F3"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2008-10-01</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>J</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>518690</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>2.5400</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>93211</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By ALSF II (QP), LP</value>
                    <footnoteId id="F4"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2008-10-01</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>J</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>138943</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>2.5400</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>673894</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By ALSF II, LP</value>
                    <footnoteId id="F5"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2008-10-01</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>J</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>386127</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>2.5400</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1138381</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By ALSF, LP</value>
                    <footnoteId id="F6"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">On October 1, 2008, Accipiter Life Sciences Fund II (Offshore), Ltd. and Accipiter Life Sciences Fund II (QP), LP transferred shares to Accipiter Life Sciences Fund (Offshore), Ltd., Accipiter Life Sciences Fund, LP and Accipiter Life Sciences Fund II, LP.  The prices disclosed in the table above reflect the closing price of the Issuer's Common Stock on September 30, 2008.</footnote>
        <footnote id="F2">Held by Accipiter Life Sciences Fund (Offshore), Ltd.  Accipiter Capital Management, LLC, the investment manager of Accipiter Life Sciences Fund (Offshore), Ltd. and Gabe Hoffman, the managing member of Accipiter Capital Management, LLC, disclaim beneficial ownership of these securities except to the extent of their pecuniary interest therein.</footnote>
        <footnote id="F3">Held by Accipiter Life Sciences Fund II (Offshore), Ltd.  Accipiter Capital Management, LLC, the investment manager of Accipiter Life Sciences Fund II (Offshore), Ltd. and Gabe Hoffman, the managing member of Accipiter Capital Management, LLC, disclaim beneficial ownership of these securities except to the extent of their pecuniary interest therein.</footnote>
        <footnote id="F4">Held by Accipter Life Sciences Fund II (QP), LP.  Candens Capital, LLC, the general partner of Accipter Life Sciences Fund II (QP), LP and Gabe Hoffman, the managing member of Candens Capital, LLC, disclaim beneficial ownership of these securities except to the extent of their pecuniary interest therein.</footnote>
        <footnote id="F5">Held by Accipiter Life Sciences Fund II, LP.  Candens Capital, LLC, the general partner of Accipiter Life Sciences Fund II, LP and Gabe Hoffman, the managing member of Candens Capital, LLC, disclaim beneficial ownership of these securities except to the extent of their pecuniary interest therein.</footnote>
        <footnote id="F6">Held by Accipiter Life Sciences Fund, LP.  Candens Capital, LLC, the general partner of Accipiter Life Sciences Fund, LP and Gabe Hoffman, the managing member of Candens Capital, LLC, disclaim beneficial ownership of these securities except to the extent of their pecuniary interest therein.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>By: Accipiter Capital Management, LLC; By: /s/ Gabe Hoffman, Managing Member</signatureName>
        <signatureDate>2008-10-03</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>By: Accipiter Life Sciences Fund II, LP; By: Candens Capital, LLC, its General Partner; By: /s/ Gabe Hoffman, Managing Member</signatureName>
        <signatureDate>2008-10-03</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>By: Accipiter Life Sciences Fund II (Offshore), Ltd.; By: Accipiter Capital Management, LLC, its Investment Manager; By: /s/ Gabe Hoffman, Managing Member</signatureName>
        <signatureDate>2008-10-03</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>By: Accipiter Life Sciences Fund II (QP), LP; By: Candens Capital, LLC, its General Partner; By: /s/ Gabe Hoffman, Managing Member</signatureName>
        <signatureDate>2008-10-03</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>By: Accipiter Life Sciences Fund, LP; By: Candens Capital, LLC, its General Partner; By: /s/ Gabe Hoffman, Managing Member</signatureName>
        <signatureDate>2008-10-03</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>By: Accipiter Life Sciences Fund (Offshore), Ltd.; By: Accipiter Capital Management, LLC, its Investment Manager; By: /s/ Gabe Hoffman, Managing Member</signatureName>
        <signatureDate>2008-10-03</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>By: Candens Capital, LLC; By: /s/ Gabe Hoffman, Managing Member</signatureName>
        <signatureDate>2008-10-03</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>By: /s/ Gabe Hoffman</signatureName>
        <signatureDate>2008-10-03</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----