Exhibit 12.1

Simmons First National Corporation
Computation of Consolidated Ratios of Earnings to Fixed Charges
	Three Months Ended
	March 31,				Year Ended December 31,
	2010		2009		2009		2008		2007		2006		2005
Fixed Charges:
Interest on deposits	$	5,437	$	9,503	$	31,046	$	53,150	$	65,474	$	54,250	$	34,208
Interest on borrowings		1,737		1,997		7,760		8,974		10,946		10,308		8,606
Estimated interest on rental expense		119		119		469		487		566		541		525
Fixed charges including interest on deposits (A)		7,293		11,619		39,275		62,611		76,986		65,099		43,339
Less: Interest on deposits		5,437		9,503		31,046		53,150		65,474		54,250		34,208
Fixed charges excluding interest on deposits (B)	$	1,856	$	2,116	$	8,229	$	9,461	$	11,512	$	10,849	$	9,131
Earnings:
Pretax income from continuing operations	$	6,585	$	7,056	$	35,400	$	38,337	$	39,741	$	39,921	$	39,465
Fixed charges including interest on deposits		7,293		11,619		39,275		62,611		76,986		65,099		43,339
Earnings, including interest on deposits (C)		13,878		18,675		74,675		100,948		116,727		105,020		82,804
Less: Interest on deposits		5,437		9,503		31,046		53,150		65,474		54,250		34,208
Earnings, excluding interest on deposits (D)	$	8,441	$	9,172	$	43,629	$	47,798	$	51,253	$	50,770	$	48,596
Ratio of earnings to fixed charges:
Including interest on deposits (C /A)		1.90		1.61		1.90		1.61		1.52		1.61		1.91
Excluding interest on deposits (D / B)		4.55		4.33		5.30		5.05		4.45		4.68		5.32