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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 JimWONg59X9imIwQQSqk5B5FB6DZi2nRLsh+fFU/ggopKAH1iMvDDT5eKnGT87eQ
 Ij4t5k6BQgWx03F4T9cnSw==

<SEC-DOCUMENT>0001082504-05-000080.txt : 20051230
<SEC-HEADER>0001082504-05-000080.hdr.sgml : 20051230
<ACCEPTANCE-DATETIME>20051230153654
ACCESSION NUMBER:		0001082504-05-000080
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20051230
FILED AS OF DATE:		20051230
DATE AS OF CHANGE:		20051230

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			KIMBERLIN KEVIN
		CENTRAL INDEX KEY:			0000904841

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-18006
		FILM NUMBER:		051294522

	BUSINESS ADDRESS:	
		STREET 1:		SPENCER TRASK SECURITIES INC
		STREET 2:		535 MADISON AVENUE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		2123555565

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			IMMUNE RESPONSE CORP
		CENTRAL INDEX KEY:			0000817785
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				330255679
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		5931 DARWIN COURT
		CITY:			CARLSBAD
		STATE:			CA
		ZIP:			92008
		BUSINESS PHONE:		7604317080

	MAIL ADDRESS:	
		STREET 1:		5931 DARWIN COURT
		CITY:			CARLSBAD
		STATE:			CA
		ZIP:			92008
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>primary_doc.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2005-12-30</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000817785</issuerCik>
        <issuerName>IMMUNE RESPONSE CORP</issuerName>
        <issuerTradingSymbol>IMNR</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0000904841</rptOwnerCik>
            <rptOwnerName>KIMBERLIN KEVIN</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>535 MADISON AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10022</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock, par value $0.0025 per share</value>
            </securityTitle>
            <transactionDate>
                <value>2005-12-30</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>3496000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F1"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>14208284</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Note</value>
                    <footnoteId id="F2"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">2,620,560 shares of the Issuer's Common Stock, the resale of which is not subject to a registration statement, were sold at a price of $0.049 per share, and 875,440 shares of the Issuer's Common Stock, the resale of which is subject to the Issuer's registration statement on Form S-3 (file number 333-101856), were sold at a price of $0.074 per share.</footnote>
        <footnote id="F2">The securities reported in Table I, Column 4 were sold, and the securities reported in Table I, Column 5 are held, by Cheshire Associates, LLC (&quot;Cheshire&quot;), a related party of the reporting person.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Kevin B. Kimberlin</signatureName>
        <signatureDate>2005-12-30</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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