EXHIBIT 99.85


          THE  SECURITIES  REPRESENTED  HEREBY  HAVE  BEEN  ISSUED  WITHOUT
          REGISTRATION  UNDER THE  SECURITIES  ACT OF 1933, AS AMENDED,  OR
          UNDER ANY STATE SECURITIES LAWS, AND MAY NOT BE SOLD, TRANSFERRED
          OR PLEDGED IN THE ABSENCE OF AN EFFECTIVE  REGISTRATION STATEMENT
          UNDER APPLICABLE  FEDERAL AND STATE SECURITIES LAWS OR AN OPINION
          OF  COUNSEL  REASONABLY  SATISFACTORY  TO THE  COMPANY  THAT  THE
          TRANSFER IS EXEMPT FROM REGISTRATION UNDER APPLICABLE FEDERAL AND
          STATE SECURITIES LAWS.


                         VYTERIS HOLDINGS (NEVADA), INC.
                         10% CONVERTIBLE PROMISSORY NOTE


$500,000                                                   Fair Lawn, New Jersey
                                                                  August 2, 2006


            FOR VALUE RECEIVED,  the  undersigned,  Vyteris  Holdings  (Nevada),
Inc., a Nevada corporation (the "Issuer"),  hereby  unconditionally  promises to
pay,  in  accordance  with the  Note  Purchase  Agreement  (the  "Note  Purchase
Agreement"),  dated as of the date hereof, by and between the Issuer and Spencer
Trask  Specialty  Group,   LLC,  a  Delaware  limited   liability  company  (the
"Purchaser"),  on the Maturity Date (as defined in the Note Purchase  Agreement)
to the order of the  Purchaser,  at the office of the  Purchaser  located at 535
Madison Avenue,  New York, NY or such other address designated by the Purchaser,
in lawful  money of the United  States of America and in  immediately  available
funds,  the principal amount of Five Hundred Thousand  ($500,000)  Dollars.  The
Issuer further agrees to pay interest on the unpaid principal amount outstanding
hereunder  from time to time from the date hereof in like money at the rates and
as and on the dates specified in Section 3.3 of the Note Purchase Agreement.

            This Note is the  promissory  note  referred to in the Note Purchase
Agreement,  and is entitled to the benefits thereof, and is subject to voluntary
and  mandatory   conversions   as  set  forth   therein.   This  Note,  and  all
representations,  warranties,  covenants and agreements  contained herein and in
the Note Purchase Agreement, shall be binding upon Issuer and its successors and
permitted  assigns  and shall  inure to the  benefit  of the  Purchaser  and its
successors  and assigns.  Issuer may not assign or delegate any of its duties or
obligations under this Note without the written consent of the Purchaser,  which
shall not be unreasonably withheld.

            Upon the  occurrence  of any one or more of the  Events  of  Default
specified in the Note Purchase  Agreement,  all amounts then remaining unpaid on
this Note shall become,  or may be declared to be,  immediately due and payable,
all as provided in the Note Purchase Agreement.

            All parties  now and  hereafter  liable  with  respect to this Note,
whether maker, principal, surety, guarantor, endorser or otherwise, hereby waive
presentment, demand, protest and all other notices of any kind.





            Subject to Sections 3.3 and 10.5 of the Note Purchase Agreement, the
Issuer  agrees  to pay all of the  Purchaser's  expenses,  including  reasonable
attorneys' costs and fees, incurred in collecting sums due under this Note.

            This Note shall be governed by, and  construed  and  interpreted  in
accordance with, the laws of the State of New York.


                              VYTERIS HOLDINGS (NEVADA), INC.


                              By: /s/ Timothy McIntyre
                                  --------------------------------------
                                  Name:  Timothy McIntyre
                                  Title: Chief Executive Officer













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