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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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<SEC-DOCUMENT>0001013594-08-000525.txt : 20080826
<SEC-HEADER>0001013594-08-000525.hdr.sgml : 20080826
<ACCEPTANCE-DATETIME>20080826164855
ACCESSION NUMBER:		0001013594-08-000525
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20080822
FILED AS OF DATE:		20080826
DATE AS OF CHANGE:		20080826

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ISCO INTERNATIONAL INC
		CENTRAL INDEX KEY:			0000888693
		STANDARD INDUSTRIAL CLASSIFICATION:	INSTRUMENTS FOR MEAS & TESTING OF ELECTRICITY & ELEC SIGNALS [3825]
		IRS NUMBER:				363688459
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		1001 CAMBRIDGE DRIVE
		CITY:			ELK GROVE VILLAGE
		STATE:			IL
		ZIP:			60007
		BUSINESS PHONE:		8473919400

	MAIL ADDRESS:	
		STREET 1:		1001 CAMBRIDGE DRIVE
		CITY:			ELK GROVE VILLAGE
		STATE:			IL
		ZIP:			60007

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			ELLIOTT ASSOCIATES, L.P.
		CENTRAL INDEX KEY:			0000904495
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-22302
		FILM NUMBER:		081039774

	BUSINESS ADDRESS:	
		STREET 1:		712 FIFTH AVENUE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10019
		BUSINESS PHONE:		2125062999

	MAIL ADDRESS:	
		STREET 1:		712 FIFTH AVE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10019

	FORMER NAME:	
		FORMER CONFORMED NAME:	ELLIOTT ASSOCIATES LP
		DATE OF NAME CHANGE:	19930513
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>iscofm4-082608_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2008-08-22</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000888693</issuerCik>
        <issuerName>ISCO INTERNATIONAL INC</issuerName>
        <issuerTradingSymbol>ISO</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0000904495</rptOwnerCik>
            <rptOwnerName>ELLIOTT ASSOCIATES, L.P.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>712 FIFTH AVE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10019</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>9 1/2% Secured Convertible Note Due August 1, 2010</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.20</value>
                <footnoteId id="F1"/>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2008-08-22</value>
                <footnoteId id="F2"/>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionTotalValue>
                    <value>450000</value>
                    <footnoteId id="F2"/>
                </transactionTotalValue>
                <transactionPricePerShare>
                    <value>450000</value>
                    <footnoteId id="F2"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2008-08-22</value>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <value>2010-08-01</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>2250000</value>
                    <footnoteId id="F2"/>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <valueOwnedFollowingTransaction>
                    <value>450000</value>
                    <footnoteId id="F2"/>
                </valueOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See</value>
                    <footnoteId id="F3"/>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">On August 18, 2008, the issuer issued to Manchester Securities Corp. (&quot;Manchester&quot;), a wholly-owned subsidiary of Elliott
 Associates, L.P. (&quot;Elliott Associates&quot;) a 9 1/2% Secured Convertible Note Due August 1, 2010 (the &quot;Convertible Note&quot;).  The
 issuer can draw down on the Convertible Note up to $1,350,000.  The Convertible Note is convertible into shares of common
 stock at a conversion price of $0.20 per share.  The Convertible Note converts into shares of common stock at a rate
 determined by dividing the then outstanding principal amount by the then conversion price.  Accrued interest is added to the
 outstanding principal amount.  The number of shares into which the Convertible Note converts shall be adjusted according to
 typical anti-dilution provisions.  More information about the Convertible Notes can be found in the Form 8-K filed by the
 issuer with the Securities and Exchange Commission on August 18, 2008.</footnote>
        <footnote id="F2">On August 22, 2008, the issuer drew down $450,000 on the Convertible Note.  This $450,000 is convertible into 2,250,000
 shares of common stock.</footnote>
        <footnote id="F3">Elliott Associates owns the Convertible Note reported on this Form 4 indirectly through Manchester.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>Elliot Greenberg, VP of Braxton Associates, Inc., as GP of Elliott Capital Advisors, L.P., as GP of Elliott Associates, L.P.</signatureName>
        <signatureDate>2008-08-26</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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