SEC FORM 4

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person^*

Bateson Susan D.

(Last)

(First)

(Middle)

14200 SHADY GROVE ROAD

(Street)

ROCKVILLE

20850

(City)

(State)

(Zip)

2. Issuer Name and Ticker or Trading Symbol
HUMAN GENOME SCIENCES INC [ HGSI ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director	10% Owner
X	Officer (give title below)	Other (specify below)
	Senior Vice President

3. Date of Earliest Transaction (Month/Day/Year)
01/04/2010

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	Amount	(A) or (D)	Price		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
Common Stock	01/04/2010		M		4,500	A	$4.92	64,858	D
Common Stock	01/04/2010		M		3,832	A	$10.89	68,690	D
Common Stock	01/04/2010		M		3,800	A	$12.56	72,490	D
Common Stock	01/04/2010		M		1,500	A	$10.62	73,990	D
Common Stock	01/04/2010		M		1,200	A	$10.62	75,190	D
Common Stock	01/04/2010		M		1,000	A	$12.56	76,190	D
Common Stock	01/04/2010		M		1,000	A	$10.89	77,190	D
Common Stock	01/04/2010		M		968	A	$10.89	78,158	D
Common Stock	01/04/2010		M		500	A	$10.62	78,658	D
Common Stock	01/04/2010		M		300	A	$4.92	78,958	D
Common Stock	01/04/2010		M		200	A	$12.56	79,158	D
Common Stock	01/04/2010		M		200	A	$12.56	79,358	D
Common Stock	01/04/2010		M		200	A	$12.56	79,558	D
Common Stock	01/04/2010		M		200	A	$12.56	79,758	D
Common Stock	01/04/2010		M		200	A	$10.89	79,958	D
Common Stock	01/04/2010		M		200	A	$10.89	80,158	D
Common Stock	01/04/2010		M		100	A	$12.56	80,258	D
Common Stock	01/04/2010		M		100	A	$12.56	80,358	D
Common Stock	01/04/2010		S⁽¹⁾		100	D	$30.9575	80,258	D
Common Stock	01/04/2010		S⁽¹⁾		100	D	$30.7	80,158	D
Common Stock	01/04/2010		S⁽¹⁾		200	D	$30.93	79,958	D
Common Stock	01/04/2010		S⁽¹⁾		200	D	$30.9	79,758	D
Common Stock	01/04/2010		S⁽¹⁾		200	D	$30.89	79,558	D
Common Stock	01/04/2010		S⁽¹⁾		200	D	$30.89	79,358	D
Common Stock	01/04/2010		S⁽¹⁾		200	D	$30.87	79,158	D
Common Stock	01/04/2010		S⁽¹⁾		200	D	$30.715	78,958	D
Common Stock	01/04/2010		S⁽¹⁾		300	D	$30.86	78,658	D
Common Stock	01/04/2010		S⁽¹⁾		500	D	$30.784	78,158	D
Common Stock	01/04/2010		S⁽¹⁾		968	D	$30.7186	77,190	D
Common Stock	01/04/2010		S⁽¹⁾		1,000	D	$30.95	76,190	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	8. Price of Derivative Security (Instr. 5)		10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
Employee Stock Option - Right to Buy	$12.56	01/04/2010		M			100	⁽²⁾	01/17/2015	Common Stock	100	$0	74,954	D
Employee Stock Option - Right to Buy	$12.56	01/04/2010		M			100	⁽²⁾	01/17/2015	Common Stock	100	$0	75,054	D
Employee Stock Option - Right to Buy	$12.56	01/04/2010		M			200	⁽²⁾	01/17/2015	Common Stock	200	$0	74,754	D
Employee Stock Option - Right to Buy	$12.56	01/04/2010		M			200	⁽²⁾	01/17/2015	Common Stock	200	$0	74,154	D
Employee Stock Option - Right to Buy	$12.56	01/04/2010		M			200	⁽²⁾	01/17/2015	Common Stock	200	$0	74,354	D
Employee Stock Option - Right to Buy	$12.56	01/04/2010		M			200	⁽²⁾	01/17/2015	Common Stock	200	$0	74,554	D
Employee Stock Option - Right to Buy	$12.56	01/04/2010		M			1,000	⁽²⁾	01/17/2015	Common Stock	1,000	$0	73,154	D
Employee Stock Option - Right to Buy	$12.56	01/04/2010		M			3,800	⁽²⁾	01/17/2015	Common Stock	3,800	$0	69,354	D
Employee Stock Option - Right to Buy	$10.89	01/04/2010		M			200	⁽³⁾	03/14/2016	Common Stock	200	$0	14,320	D
Employee Stock Option - Right to Buy	$10.89	01/04/2010		M			200	⁽³⁾	03/14/2016	Common Stock	200	$0	14,520	D
Employee Stock Option - Right to Buy	$10.89	01/04/2010		M			968	⁽³⁾	03/14/2016	Common Stock	968	$0	13,352	D
Employee Stock Option - Right to Buy	$10.89	01/04/2010		M			1,000	⁽³⁾	03/14/2016	Common Stock	1,000	$0	12,352	D
Employee Stock Option - Right to Buy	$10.89	01/04/2010		M			3,832	⁽³⁾	03/14/2016	Common Stock	3,832	$0	8,520	D
Employee Stock Option - Right to Buy	$10.62	01/04/2010		M			500	⁽⁴⁾	03/10/2017	Common Stock	500	$0	20,332	D
Employee Stock Option - Right to Buy	$10.62	01/04/2010		M			1,200	⁽⁴⁾	03/10/2017	Common Stock	1,200	$0	19,132	D
Employee Stock Option - Right to Buy	$10.62	01/04/2010		M			1,500	⁽⁴⁾	03/10/2017	Common Stock	1,500	$0	17,632	D
Employee Stock Option - Right to Buy	$4.92	01/04/2010		M			300	⁽⁵⁾	03/10/2018	Common Stock	300	$0	68,804	D
Employee Stock Option - Right to Buy	$4.92	01/04/2010		M			4,500	⁽⁵⁾	03/10/2018	Common Stock	4,500	$0	64,304	D

Explanation of Responses:

1. The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person and Charles Schwab effective 12/10/09.

2. One-eighth of the options granted on January 17, 2005 vested on the six-month anniversary date (July 17, 2005) and the remaining options granted vested monthly on a ratable basis for the next 42 months commencing on August 17, 2005.

3. One-eighth of the options granted on March 14, 2006 vested on the six-month anniversary date (Sept 14, 2006) and the remaining options granted vested and continue to vest monthly on a ratable basis for the next 42 months commencing on October14, 2006.

4. One-eighth of the options granted on March 10, 2007 vested on the six-month anniversary date (Sept 10, 2007) and the remaining options granted vested and continue to vest monthly on a ratable basis for the next 42 months commencing on October10, 2007.

5. One-eighth of the options granted on March 10, 2008 vested on the six-month anniversary date (Sept 10, 2008) and the remaining options granted vested and continue to vest monthly on a ratable basis for the next 42 months commencing on October10, 2008.

Remarks:

Multiple Forms submitted.

	James H. Davis, Pursuant to Power of Attorney	01/06/2010
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
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