Acquisitions (Narrative) (Details) (USD $)	3 Months Ended	6 Months Ended
Jun. 30, 2011	Jun. 30, 2011	Feb. 28, 2011
Costs related to the acquisition	$ 1,000,000	$ 10,928,000
Contingent consideration	17,601,000	17,601,000
Increase in fair value of contingent consideration		881,000
Taligen Therapeutics, Inc [Member] \| Purchased Technology [Member]
Intangible assets	5,000,000	5,000,000
Taligen Therapeutics, Inc [Member] \| In-process Research and Development [Member]
Non-amortizable intangible assets	59,500,000	59,500,000
Orphatec Pharmaceuticals GmbH [Member] \| In-process Research and Development [Member]
Non-amortizable intangible assets	8,050,000	8,050,000
Taligen Therapeutics, Inc [Member] \| Maximum [Member]
Contingent milestone payments	367,000,000	367,000,000
Orphatec Pharmaceuticals GmbH [Member] \| Maximum [Member]
Contingent milestone payments	42,000,000	42,000,000
Taligen Therapeutics, Inc [Member] \| Minimum [Member]
Contingent milestone payments	0	0
Orphatec Pharmaceuticals GmbH [Member] \| Minimum [Member]
Contingent milestone payments	0	0
Taligen Therapeutics, Inc [Member]
Initial payments on acquisition	111,773,000	111,773,000
Contingent milestone payments	367,000,000	367,000,000
Costs related to the acquisition	707,000	10,076,000
Fair value of contingent consideration	11,634,000	11,634,000
Rate for discounting contingent consideration cash flows		4.90%
Contingent consideration	12,384,000	12,384,000
Increase in fair value of contingent consideration	1,321,000
Purchased technology, estimated useful life (In years)		12
Rate of return on historical costs		25.00%
Deferred tax liability	9,959,000	9,959,000
Deferred tax liability related to IPR&D	21,537,000	21,537,000
Deferred tax liability related to net operating losses and research credit carryovers	13,338,000	13,338,000
Orphatec Pharmaceuticals GmbH [Member]
Initial payments on acquisition	3,050,000	3,050,000	3,050,000
Contingent milestone payments	42,000,000	42,000,000
Costs related to the acquisition	293,000	852,000
Fair value of contingent consideration	5,086,000	5,086,000
Contingent consideration	$ 5,217,000	$ 5,217,000
Weighted cash flow discount rate for development milestones		4.90%
Weighted cash flow discount rate for commercial milestones		21.00%
Present value discount rate		23.00%

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