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Acquisitions (Summary of Total Consideration) (Details) - USD ($)
$ in Millions
3 Months Ended
Jul. 02, 2020
Jan. 28, 2020
Mar. 31, 2021
Mar. 31, 2020
Dec. 31, 2020
Consideration          
Upfront payment, fair value of equity compensation attributable to the post-combination service period     $ 0.0 $ (25.7)  
Contingent consideration     303.5   $ 299.4
Assets Acquired and Liabilities Assumed          
Goodwill     5,100.1   $ 5,100.1
Portola Pharmaceuticals          
Consideration          
Fair value of equity shares held by Alexion at closing $ 47.8        
Achillion          
Consideration          
Upfront payment to shareholders and option holders   $ 926.2      
Upfront payment, fair value of equity compensation attributable to the post-combination service period   (20.0)   $ (25.7)  
Upfront cash paid, net   906.2      
Contingent consideration   160.7 $ 212.8    
Contingent consideration, fair value of equity compensation attributable to the post-combination service period   (5.7)      
Total consideration   1,061.2      
Assets Acquired and Liabilities Assumed          
Cash and cash equivalents   68.5      
Marketable securities   106.1      
Deferred tax assets, net   142.4      
Goodwill   37.8      
Deferred tax liabilities, net   (62.9)      
Other assets and liabilities, net   (6.3)      
Total net assets acquired   1,061.2      
Portola Pharmaceuticals, Inc.          
Consideration          
Upfront payment to shareholders and option holders 1,380.8        
Upfront payment, fair value of equity compensation attributable to the post-combination service period (11.1)        
Upfront cash paid, net 1,369.7        
Fair value of replacement equity awards attributable to the pre-combination period 7.2        
Total consideration to acquire outstanding equity, net 1,424.7        
Repayments of debt 196.9        
Total consideration 1,621.6        
Assets Acquired and Liabilities Assumed          
Cash and cash equivalents 288.5        
Marketable securities 17.8        
Inventories, including noncurrent portion of $169.1 and validation batches of $60.9 362.5        
Noncurrent inventory 169.1        
Validation batches 60.9        
Intangible assets 1,051.0        
Deferred tax assets, net 116.6        
Other assets 41.9        
Goodwill 24.9        
Accounts payable and accrued expenses (75.6)        
Long-term debt, including current portion of $7.7 (182.0)        
Current debt 7.7        
Other liabilities (24.0)        
Total net assets acquired 1,621.6        
In-process research & development assets (IPR&D) | Achillion          
Assets Acquired and Liabilities Assumed          
In-process research & development assets (IPR&D)   918.0      
Deferred tax liabilities, net   $ (205.3)      
In-process research & development assets (IPR&D) | Portola Pharmaceuticals, Inc.          
Assets Acquired and Liabilities Assumed          
In-process research & development assets (IPR&D) $ 15.0