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Commitments and Contingencies (Narrative) (Details) - USD ($)
$ in Millions
1 Months Ended 3 Months Ended 6 Months Ended 9 Months Ended
Jul. 02, 2020
Dec. 31, 2019
Sep. 30, 2019
Apr. 30, 2019
Mar. 31, 2019
Jan. 31, 2019
Nov. 30, 2018
Oct. 31, 2018
Sep. 30, 2020
Jun. 30, 2020
Dec. 31, 2019
Sep. 30, 2019
Mar. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Sep. 30, 2020
Sep. 30, 2020
Sep. 30, 2019
Oct. 27, 2020
Other Commitments [Line Items]                                      
Asset Acquisition, Contingent Consideration, Milestone Payments                                 $ 160.7    
Research and development                 $ 285.9     $ 232.9         707.9 $ 616.4  
Lonza Group AG                                      
Other Commitments [Line Items]                                      
Remaining total commitments                 1,432.3             $ 1,432.3 1,432.3    
Unrecorded Unconditional Purchase Obligation, Undiscounted Fixed Payment Amount                 105.5             105.5 105.5    
Other Third Party Manufacturers                                      
Other Commitments [Line Items]                                      
Remaining total commitments                 78.6             78.6 78.6    
Collaborative Arrangement | Caelum                                      
Other Commitments [Line Items]                                      
Collaboration Agreement, Upfront Payment           $ 30.0                          
Research and development                 3.6     0.2         6.0 $ 0.5  
Collaboration Agreement, Potential Future Payments, Milestone Achievement           30.0     15.0                    
Derivative Liability   $ 27.1                 $ 27.1                
Collaboration Agreement, Acquisition Option, Maximum Potential Future Payment           500.0                          
Collaboration Agreement, Milestone Payment                   $ 15.0           30.0      
Collaboration Agreement, Potential Future Payments                     20.0                
Collaboration Agreement, Payment For Additional Equity Interest   $ 60.0                                  
Zealand | Zealand                                      
Other Commitments [Line Items]                                      
Payments To Acquire Licenses And Equity Investment         $ 40.0                            
Prepaid Research And Development Expense         5.0               $ 5.0            
Research and development                         $ 21.2            
Collaboration Agreement, Potential Future Payments, Milestone Achievement                                 610.0    
Collaboration Agreement, Potential Future Payments, Additional Milestone Achievement                                 115.0    
Collaboration Agreement, Potential Future Payments, Option Fee                                 15.0    
Affibody AB | Affibody                                      
Other Commitments [Line Items]                                      
Payments To Acquire Licenses And Equity Investment       $ 25.0                              
Affibody AB | Eidos                                      
Other Commitments [Line Items]                                      
Payments To Acquire Licenses And Equity Investment     $ 50.0                                
Research and development                       $ 30.1              
Collaboration Agreement, Potential Future Payments, Milestone Achievement                                 30.0    
Dicerna Pharmaceutical Collaboration Agreement | Dicerna                                      
Other Commitments [Line Items]                                      
Payments To Acquire Licenses And Equity Investment               $ 37.0                      
Research and development                     $ 20.0     $ 26.7          
Research and Development Arrangement, Potential Payment, Maximum                 604.1             604.1 604.1    
License Agreement 1 | Halozyme Therapeutics, Inc                                      
Other Commitments [Line Items]                                      
Research and Development Arrangement, Potential Payment, Maximum                 155.0             155.0 155.0    
Research and development                             $ 40.0        
Research and Development Agreement, Option Fee                 8.0             8.0 8.0    
Research and Development Arrangement, Potential Contingent Payment, Maximum                 160.0             160.0 160.0    
Collaboration and License Agreement                                      
Other Commitments [Line Items]                                      
Collaboration Agreement, Potential Future Payments, Milestone Achievement                                 114.0    
Eidos                                      
Other Commitments [Line Items]                                      
Payments to Acquire Equity Method Investments     $ 19.9                                
Caelum | Collaborative Arrangement                                      
Other Commitments [Line Items]                                      
Equity Method Investment, Aggregate Cost           $ 57.1                          
Zealand                                      
Other Commitments [Line Items]                                      
Payments to Acquire Equity Method Investments         $ 13.8                            
Dicerna                                      
Other Commitments [Line Items]                                      
Payments to Acquire Equity Method Investments               $ 10.3                      
SEC                                      
Other Commitments [Line Items]                                      
Litigation Settlement, Amount Awarded to Other Party $ 21.5                                    
DOJ And OIG                                      
Other Commitments [Line Items]                                      
Loss Contingency Accrual, Payments       $ 13.1                              
Canadian Patented Medicine Prices Review Board                                      
Other Commitments [Line Items]                                      
Loss Contingency, Estimate of Possible Loss                 42.2             $ 42.2 $ 42.2    
Syntimmune, Inc                                      
Other Commitments [Line Items]                                      
Asset Acquisition, Contingent Consideration, Milestone Payments             $ 800.0                        
Syntimmune, Inc | Subcutaneous Formulation                                      
Other Commitments [Line Items]                                      
Asset Acquisition, Contingent Consideration, Milestone Payments             $ 130.0                        
Astellas Pharam [Member]                                      
Other Commitments [Line Items]                                      
Asset Acquisition, Contingent Consideration, Milestone Payments                 $ 71.5                    
Subsequent Event | Canadian Patented Medicine Prices Review Board                                      
Other Commitments [Line Items]                                      
Escrow Deposit                                     $ 61.5