Condensed Consolidated Statements of Operations - USD ($) shares in Millions, $ in Millions	3 Months Ended		9 Months Ended
	Sep. 30, 2020	Sep. 30, 2019	Sep. 30, 2020	Sep. 30, 2019
Total revenues	$ 1,588.7	$ 1,263.1	$ 4,478.1	$ 3,606.8
Costs and expenses:
Cost of sales (exclusive of amortization of purchased intangible assets)	144.7	95.2	401.3	280.2
Research and development	285.9	232.9	707.9	616.4
Selling, general and administrative	334.2	299.3	955.5	880.1
Acquired in-process research and development	0.0	0.0	0.0	(4.1)
Amortization of purchased intangible assets	53.1	75.6	200.5	235.7
Change in fair value of contingent consideration	23.4	29.8	45.0	7.2
Acquisition-related costs	63.0	0.0	105.7	0.0
Restructuring expenses	14.3	0.3	13.5	11.9
Impairment of intangible assets	0.0	0.0	2,053.3	0.0
Gain on sale of asset	(14.8)	0.0	(14.8)	0.0
Total costs and expenses	903.8	733.1	4,467.9	2,027.4
Operating income	684.9	530.0	10.2	1,579.4
Other income and expense:
Investment income, net	11.5	23.0	47.8	50.6
Interest expense	(27.6)	(17.9)	(77.0)	(56.1)
Other income and (expense)	(1.9)	0.4	(2.6)	2.9
Income (loss) before income taxes	666.9	535.5	(21.6)	1,576.8
Income tax expense (benefit)	88.8	67.9	(89.2)	61.5
Net income	$ 578.1	$ 467.6	$ 67.6	$ 1,515.3
Earnings per common share
Basic (in dollars per share)	$ 2.64	$ 2.09	$ 0.31	$ 6.77
Diluted (in dollars per share)	$ 2.62	$ 2.08	$ 0.30	$ 6.72
Shares used in computing earnings per common share
Basic	219.1	223.3	220.4	223.8
Diluted	220.6	224.5	221.9	225.4
Net product sales
Total revenues	$ 1,588.3	$ 1,263.1	$ 4,477.4	$ 3,605.8
Other revenue
Total revenues	$ 0.4	$ 0.0	$ 0.7	$ 1.0