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Restructuring and Related Expenses
12 Months Ended
Dec. 31, 2019
Restructuring and Related Activities [Abstract]  
Restructuring and Related Expenses
Restructuring and Related Expenses
In the first quarter 2019, we initiated corporate restructuring activities to re-align our international commercial organization through re-prioritization of certain geographical markets and to implement operational excellence through strategic reallocation of resources.
In the first quarter 2017, we initiated a company-wide restructuring designed to help position the Company for sustainable, long-term growth that we believe will further allow us to fulfill our mission of serving patients and families with rare diseases. In September 2017, we committed to an operational plan to re-align the global organization with its refocused corporate strategy. The re-alignment included the relocation of the Company's headquarters to Boston, Massachusetts and a reduction of the Company's global workforce. The restructuring was designed to result in cost
savings by focusing the development portfolio, simplifying business structures and process across the Company's global operations, and closing multiple Alexion sites.
The following table summarizes the total expenses recorded related to the restructuring activities by type of activity and the locations recognized within the consolidated statements of operations:

December 31, 2019

December 31, 2018
 
December 31, 2017

Employee Separation Costs
Asset-Related Charges
Other
Total

Employee Separation Costs
Asset-Related Charges
Other
Total
 
Employee Separation Costs
Asset-Related Charges
Other
Total
Cost of sales
$

$

$

$


$

$
5.8

$

$
5.8

 
$

$
152.1

$

$
152.1

Research and development






0.1


0.1

 

16.3


16.3

Selling, general and administrative






19.4


19.4

 

10.9


10.9

Restructuring expenses
8.4


3.6

12.0


4.6


20.9

25.5

 
87.3


17.3

104.6

Other income and (expense)







(0.1
)
(0.1
)
 


2.6

2.6


$
8.4

$

$
3.6

$
12.0


$
4.6

$
25.3

$
20.8

$
50.7

 
$
87.3

$
179.3

$
19.9

$
286.5


Employee separation costs are associated with headcount reductions, as well as corporate employees not relocating to the Company's headquarters in 2018.
Asset-related charges consist of accelerated depreciation costs and asset impairment charges. Accelerated depreciation costs primarily relates to site closures, including ARIMF (which was sold to a third-party in 2018). Accelerated depreciation costs represent the difference between the depreciation expense recognized over the revised useful life of the asset, based upon the anticipated date the site closure, and the depreciation expense as determined using the useful life prior to the restructuring activities. Asset impairment charges primarily related to manufacturing assets that will no longer be utilized due to the 2017 restructuring activities.
Other costs consist of contract termination expenses, relocation costs, and other costs incurred as a direct result of an exit plan.
The following table presents a reconciliation of the restructuring reserve recorded within accounts payable and accrued expenses on the Company's consolidated balance sheets for the years ended December 31, 2019 and 2018:
 
December 31, 2019
 
December 31, 2018
 
Employee Separation Costs
 
Asset-Related Charges
 
Other
 
Total
 
Employee Separation Costs
 
Asset-Related Charges
 
Other
 
Total
Liability, beginning of year
$
4.2

 
$

 
$

 
$
4.2

 
$
53.8

 
$

 
$
4.4

 
$
58.2

Charges
14.2

 

 
3.0

 
17.2

 
5.8

 
25.3

 
21.1

 
52.2

Settlements
(9.3
)
 

 
(0.1
)
 
(9.4
)
 
(54.2
)
 

 
(25.2
)
 
(79.4
)
Adjustments to previous estimates
(5.8
)
 

 
0.6

 
(5.2
)
 
(1.2
)
 

 
(0.3
)
 
(1.5
)
Non Cash Activity

 

 

 

 

 
(25.3
)
 

 
(25.3
)
Liability, end of year
$
3.3

 
$

 
$
3.5

 
$
6.8

 
$
4.2

 
$

 
$

 
$
4.2


The restructuring reserve of $6.8 and $4.2 is recorded in accounts payable and accrued expenses on the Company's consolidated balance sheet as of December 31, 2019 and 2018, respectively. The accrued amounts are expected to be paid in the next twelve months. We estimate incurring an immaterial amount of additional restructuring expenses relating to the first quarter 2019 action.