Facility Lease Obligations (Details) - USD ($) $ in Thousands	1 Months Ended	9 Months Ended
	Nov. 30, 2012	Sep. 30, 2016	Dec. 31, 2015
Operating Leased Assets [Line Items]
Facility Lease Obligation, Noncurrent		$ 224,442	$ 151,307
CONNECTICUT | Construction in Progress [Member]
Operating Leased Assets [Line Items]
Facility Lease Obligation		135,442	132,866
Minimum [Member] | CONNECTICUT | Construction in Progress [Member]
Operating Leased Assets [Line Items]
Lessee Leasing Arrangements, Operating Leases, Renewal Term	10 years
Lonza Group AG
Operating Leased Assets [Line Items]
Unrecorded Unconditional Purchase Obligation, Purchases		49,000
Lonza Group AG | Construction in Progress [Member]
Operating Leased Assets [Line Items]
Construction-in-process asset		100,068	19,259
Lonza Group AG | Facility Lease Obligation [Member]
Operating Leased Assets [Line Items]
Facility Lease Obligation, Noncurrent		$ 89,668	$ 15,229
Facility Lease Obligation, Payment Period		10 years
Inventories [Member] | Lonza Group AG
Operating Leased Assets [Line Items]
Unrecorded Unconditional Purchase Obligation, Purchases		$ 42,630
Facility Lease Obligation [Member] | Lonza Group AG
Operating Leased Assets [Line Items]
Unrecorded Unconditional Purchase Obligation, Purchases		$ 6,370