Restructuring (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2016	Dec. 31, 2015
Restructuring Cost and Reserve [Line Items]
Restructuring expenses	$ 452
Restructuring Reserve	3,079	$ 7,241
Employee Separation Costs
Restructuring Cost and Reserve [Line Items]
Restructuring expenses	0
Restructuring Reserve	1,436	$ 6,390
Synageva BioPharma Corp.
Restructuring Cost and Reserve [Line Items]
Restructuring expenses	(924)
Relocation of European Headquarters [Member]
Restructuring Cost and Reserve [Line Items]
Restructuring reserve, additional restructuring costs	$ 1,646