Facility Lease Obligations (Details) - USD ($) $ in Thousands	1 Months Ended	3 Months Ended
	Nov. 30, 2012	Mar. 31, 2016	Dec. 31, 2015
Operating Leased Assets [Line Items]
Facility lease obligation		$ 172,970	$ 151,307
CONNECTICUT | Facility Lease Obligation
Operating Leased Assets [Line Items]
Facility lease obligation		134,211	132,866
Minimum | CONNECTICUT | Construction in Progress
Operating Leased Assets [Line Items]
Renewal term (years)	10 years
Lonza Group AG
Operating Leased Assets [Line Items]
Unrecorded unconditional purchase obligation, purchases		23,000
Lonza Group AG | Facility Lease Obligation
Operating Leased Assets [Line Items]
Facility lease obligation		$ 35,632	15,229
Facility lease obligation, payment period (years)		10 years
Lonza Group AG | Construction in Progress
Operating Leased Assets [Line Items]
Property, plant and equipment, gross		$ 42,652	$ 19,259
Inventories | Lonza Group AG
Operating Leased Assets [Line Items]
Unrecorded unconditional purchase obligation, purchases		20,010
Facility Lease Obligation | Lonza Group AG
Operating Leased Assets [Line Items]
Unrecorded unconditional purchase obligation, purchases		$ 2,990