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Condensed Consolidated Statements of Comprehensive Income (USD $)
In Thousands, except Per Share data, unless otherwise specified
3 Months Ended 9 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Sep. 30, 2011
Net product sales $ 294,136 $ 204,047 $ 813,588 $ 555,872
Cost of sales:        
Cost of sales 33,186 23,369 93,067 64,342
Gain on intellectual property settlement (53,377) 0 (53,377) 0
Total cost of sales (20,191) 23,369 39,690 64,342
Operating expenses:        
Research and development 54,280 36,567 159,323 103,023
Selling, general and administrative 89,957 77,572 272,054 221,609
Acquisition-related costs 967 236 19,447 11,164
Impairment of acquired in-process research and development 26,300 0 26,300 0
Amortization of purchased intangible assets 104 104 312 278
Total operating expenses 171,608 114,479 477,436 336,074
Operating income 142,719 66,199 296,462 155,456
Other income and expense:        
Investment income 317 523 872 1,691
Interest expense (1,855) (204) (6,220) (605)
Foreign currency loss (416) (841) (817) (952)
Income before income taxes 140,765 65,677 290,297 155,590
Income tax provision 48,586 107 116,446 28,445
Net income 92,179 65,570 173,851 127,145
Earnings per common share        
Basic $ 0.48 $ 0.36 $ 0.92 $ 0.70
Diluted $ 0.46 $ 0.34 $ 0.88 $ 0.66
Shares used in computing earnings per common share        
Basic 193,353 183,706 189,219 182,805
Diluted 201,142 192,161 197,635 191,267
Comprehensive income $ 77,982 $ 82,093 $ 172,017 $ 131,181