Business Combination, Contingent Consideration Arrangements, Gain Related to Change of Fair Value Assumptions

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Industrial index rate for discounting contingent consideration cash flows.

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Rate of return on historical costs.

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Weighted Average Cost Of Capital Used In Discounting Contingent Consideration Cash Flows

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- Definition

Fair value, as of the acquisition date, of potential payments under the contingent consideration arrangement including cash and shares.

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Noncurrent portion of the fair value as of the acquisition date of potential payments under the contingent consideration arrangement, including cash and shares as applicable.

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Amount of potential cash payments that could result from the contingent consideration arrangement.

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Amount of cash paid to acquire the entity.

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Percentage of voting equity interests acquired in the business combination.

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The amount of acquisition cost of a business combination allocated to an identifiable intangible asset that will not be amortized. Does not include goodwill.

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This element represents acquisition-related costs incurred to effect a business combination which costs have been expensed during the period. Such costs include finder's fees; advisory, legal, accounting, valuation, and other professional or consulting fees; general administrative costs, including the costs of maintaining an internal acquisitions department; and may include costs of registering and issuing debt and equity securities.

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This element represents the amount of any change, including any differences arising upon settlement, recognized during the reporting period in the value of a liability, arising from an item of contingent consideration, assumed in a business combination.

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The expenses and losses recorded for each transaction with the acquiree that was recognized separately from the acquisition of assets and assumptions of liabilities in the business combination.

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The tax effect as of the balance sheet date of the amount of future tax deductions arising from all unused tax credit carryforwards which have been reduced by a valuation allowance.

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The cumulative amount of the estimated future tax effects attributable to the difference between the tax basis of intangible assets and the basis of intangible assets computed in accordance with generally accepted accounting principles. The difference in basis, whether due to amortization or other reasons, will increase future taxable income when such difference reverses. Intangible assets include, but are not limited to, assets such as patents, trademarks and customer lists.

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Acquisitions (Narrative) (Details) (USD $) In Thousands, unless otherwise specified	3 Months Ended		9 Months Ended			0 Months Ended	3 Months Ended	9 Months Ended	3 Months Ended		9 Months Ended			3 Months Ended		9 Months Ended										9 Months Ended
	Sep. 30, 2012	Sep. 30, 2011	Sep. 30, 2012	Sep. 30, 2011	Dec. 31, 2011	Feb. 07, 2012 Enobia Pharma Corp. [Member]	Sep. 30, 2012 Enobia Pharma Corp. [Member]	Sep. 30, 2012 Enobia Pharma Corp. [Member]	Sep. 30, 2012 Taligen Therapeutics Inc Member	Sep. 30, 2011 Taligen Therapeutics Inc Member	Sep. 30, 2012 Taligen Therapeutics Inc Member	Sep. 30, 2011 Taligen Therapeutics Inc Member	Jan. 28, 2011 Taligen Therapeutics Inc Member	Sep. 30, 2012 Orphatec Pharmaceuticals Gmbh Member	Sep. 30, 2011 Orphatec Pharmaceuticals Gmbh Member	Sep. 30, 2012 Orphatec Pharmaceuticals Gmbh Member	Sep. 30, 2011 Orphatec Pharmaceuticals Gmbh Member	Feb. 08, 2011 Orphatec Pharmaceuticals Gmbh Member	Feb. 07, 2012 Minimum [Member] Enobia Pharma Corp. [Member]	Jan. 28, 2011 Minimum [Member] Taligen Therapeutics Inc Member	Feb. 08, 2011 Minimum [Member] Orphatec Pharmaceuticals Gmbh Member	Feb. 07, 2012 Maximum [Member] Enobia Pharma Corp. [Member]	Jan. 28, 2011 Maximum [Member] Taligen Therapeutics Inc Member	Feb. 08, 2011 Maximum [Member] Orphatec Pharmaceuticals Gmbh Member	Feb. 07, 2012 In Process Research And Development Member Enobia Pharma Corp. [Member]	Sep. 30, 2012 Enobia Pharma Corp. [Member]
Business Acquisition [Line Items]
Business acquisition, cash paid						$ 623,876							$ 111,773					$ 3,050
Business Acquisition, Percentage of Voting Interests Acquired						100.00%
Business acquisition, additional contingent payments																			0	0	0	470,000	367,000	42,000
Contingent consideration	139,453		139,453		18,120	117,000	122,444	122,444	9,615		9,615			7,394		7,394
Industrial index rate for discounting contingent consideration cash flows						5.20%
Weighted Average Cost Of Capital Used In Discounting Contingent Consideration Cash Flows						13.00%
Intangible assets not amortizable																									587,000
Rate of return on historical costs						13.00%
Deferred tax liabilities						31,665
Deferred tax liabilities, intangible assets						78,620
Deferred tax assets, tax credit carryforwards						46,955
Business Combination, Separately Recognized Transactions, Expenses and Losses Recognized								6,794
Estimated fair value of contingent consideration						117,000							11,634					5,086
Change in fair value of contingent consideration							1,932	5,444	(4,224)	149	(3,069)	899		1,750	87	1,958	218
Gain related to change of fair value assumptions									4,331		4,331
Acquisition-related costs	$ 967	$ 236	$ 19,447	$ 11,164			$ 3,400	$ 20,600																		$ 7,900