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Commitments and Contingencies - Additional Information (Detail)
1 Months Ended 3 Months Ended 12 Months Ended
Aug. 31, 2019
$ / shares
shares
Dec. 31, 2018
$ / shares
shares
Nov. 30, 2017
USD ($)
May 31, 2017
USD ($)
Mar. 31, 2020
USD ($)
shares
Mar. 31, 2019
USD ($)
Jun. 30, 2018
USD ($)
Vehicle
Dec. 31, 2019
USD ($)
Vehicle
Jan. 01, 2019
USD ($)
Jul. 01, 2013
USD ($)
Commitments And Contingencies [Line Items]                    
Purchase obligation extended term 2026                  
Supply Agreement expiration period         Dec. 31, 2026          
Supply Agreement renewal period         2 years          
Operating lease, non-current liabilities         $ 2,155,000     $ 2,514,000    
Operating lease costs         400,000 $ 500,000        
Operating lease, cash paid         400,000 500,000        
Variable lease costs         $ 100,000 $ 100,000        
Operating lease, weighted average discount rate         7.50% 7.20%        
Operating lease, weighted-average remaining lease term         2 years 8 months 12 days 3 years 9 months 18 days        
Underwriting Agreement with Leerink Partners LLC                    
Commitments And Contingencies [Line Items]                    
Stock purchase agreements date   Dec. 31, 2018                
Warrants exercisable | shares         7,250,000          
Warrant expiration date         Jun. 26, 2020          
Underwriting Agreement with Leerink Partners LLC | Warrants                    
Commitments And Contingencies [Line Items]                    
Exercise price of warrants | $ / shares   $ 1.60                
Lease Agreement with Enterprise | Vehicle Leases                    
Commitments And Contingencies [Line Items]                    
Number of vehicle leases | Vehicle             119 90    
Operating lease rent expenses             $ 83,000 $ 65,000    
Number of vehicle leases removed | Vehicle               29    
Lease expiration period             48 months      
Operating lease right-of-use assets                 $ 1,600,000  
Operating lease liabilities                 1,900,000  
Operating lease, non-current other assets         $ 1,600,000          
Operating lease, other current liabilities         600,000          
Operating lease, non-current liabilities         1,300,000          
Maximum | Underwriting Agreement with Leerink Partners LLC | Warrants                    
Commitments And Contingencies [Line Items]                    
Warrants to purchase common stock | shares   26,666,667                
MidCap Credit Facility                    
Commitments And Contingencies [Line Items]                    
Warrants to purchase common stock | shares 1,171,614                  
Exercise price of warrants | $ / shares $ 1.11                  
Deerfield | Milestone Rights Liability                    
Commitments And Contingencies [Line Items]                    
Contingent liability remain payable         70,000,000          
Deerfield | Milestone Rights Liability | Maximum                    
Commitments And Contingencies [Line Items]                    
Contingent liability for milestone payments                   $ 90,000,000
Russell Ranch Road II LLC | Office Lease                    
Commitments And Contingencies [Line Items]                    
Operating lease rent expenses     $ 35,969 $ 40,951            
Operating lease right-of-use assets                 3,200,000  
Operating lease liabilities                 $ 3,500,000  
Operating lease, other current liabilities         900,000          
Operating lease, non-current liabilities         $ 2,600,000          
Percentage of annual increase in lease payment     3.00% 3.00%            
Lease expiration date     Jan. 31, 2023 Jan. 31, 2023            
Lease renewal option     5 years 5 years            
Reimbursement amount received for tenant improvements     $ 56,325