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Commitments and Contingencies - Additional Information (Detail)
$ / shares in Units, € in Millions
1 Months Ended 3 Months Ended 6 Months Ended
Dec. 19, 2018
USD ($)
$ / shares
shares
Apr. 05, 2018
$ / shares
shares
Nov. 29, 2017
USD ($)
May 05, 2017
USD ($)
Oct. 31, 2017
shares
Jun. 30, 2019
USD ($)
Vehicle
Jun. 30, 2018
USD ($)
Vehicle
Jun. 30, 2019
USD ($)
Jun. 30, 2019
EUR (€)
Jun. 30, 2018
USD ($)
Jun. 30, 2019
EUR (€)
Jan. 01, 2019
USD ($)
Jul. 01, 2013
USD ($)
Commitments And Contingencies [Line Items]                          
Purchase commitment amount under insulin supply agreement | €                 € 90.3        
Long term purchase commitment remaining amount | €                     € 82.3    
Supply Agreement expiration period               Dec. 31, 2024 Dec. 31, 2024        
Supply Agreement renewal period               2 years 2 years        
Purchase requirement amount for remaining current year | €                     € 3.9    
Operating lease, non-current liabilities           $ 3,094,000   $ 3,094,000          
Operating lease costs           300,000   800,000          
Operating lease, cash paid           200,000   700,000          
Variable lease costs           $ 100,000   $ 200,000          
Operating lease, weighted average discount rate           7.20%   7.20%     7.20%    
Operating lease, weighted-average remaining lease term           3 years 7 months 6 days   3 years 7 months 6 days     3 years 7 months 6 days    
Vehicle Leases | Lease Agreement with Enterprise                          
Commitments And Contingencies [Line Items]                          
Number of vehicle leases | Vehicle           96 119            
Operating lease rent expenses           $ 69,000 $ 83,000            
Number of vehicle leases removed | Vehicle           23              
Gain or loss recorded for leases removed           $ 0              
Lease expiration date             48 months     48 months      
Reduction in operating lease right-of-use assets           300,000   $ 300,000          
Reduction in operating lease liabilities           300,000   300,000          
Operating lease right-of-use assets                       $ 1,600,000  
Operating lease liabilities           1,300,000   1,300,000       1,600,000  
Operating lease, current assets           1,600,000   1,600,000          
Operating lease, other current liabilities           600,000   $ 600,000          
Common Stock                          
Commitments And Contingencies [Line Items]                          
Number of shares sold in underwritten public offering | shares         973,236                
Purchase Agreements                          
Commitments And Contingencies [Line Items]                          
Stock purchase agreements date   Apr. 05, 2018                      
Warrant expiration date   Apr. 09, 2019                      
Purchase Agreements | Common Stock                          
Commitments And Contingencies [Line Items]                          
Number of shares sold in underwritten public offering | shares   14,000,000                      
Exchange price per share | $ / shares   $ 2.00                      
Purchase Agreements | Warrants                          
Commitments And Contingencies [Line Items]                          
Warrants to purchase of common stock | shares   14,000,000                      
Exercise price of warrants | $ / shares   $ 2.38                      
Foreign Currency Hedging Transaction                          
Commitments And Contingencies [Line Items]                          
Foreign currency hedging transaction renewable period               90 days 90 days        
Deerfield | Milestone Rights Liability                          
Commitments And Contingencies [Line Items]                          
Contingent liability for milestone payments           75,000,000   $ 75,000,000          
Deerfield | Milestone Rights Liability | Maximum                          
Commitments And Contingencies [Line Items]                          
Contingent liability for milestone payments           $ 90,000,000   $ 90,000,000         $ 90,000,000
Leerink Partners LLC | Underwriting Agreement                          
Commitments And Contingencies [Line Items]                          
Stock purchase agreements date Dec. 26, 2018                        
Warrant expiration date Dec. 26, 2019                        
Leerink Partners LLC | Underwriting Agreement | Common Stock                          
Commitments And Contingencies [Line Items]                          
Number of shares sold in underwritten public offering | shares 26,666,667                        
Exchange price per share | $ / shares $ 1.50                        
Amount of net proceeds from issuance of securities $ 37,300,000                        
Leerink Partners LLC | Underwriting Agreement | Warrants                          
Commitments And Contingencies [Line Items]                          
Warrants to purchase of common stock | shares 26,666,667                        
Exercise price of warrants | $ / shares $ 1.60                        
Russell Ranch Road II LLC | Office Lease                          
Commitments And Contingencies [Line Items]                          
Operating lease rent expenses     $ 35,969                    
Operating lease right-of-use assets                       3,200,000  
Operating lease liabilities                       3,500,000  
Operating lease rent expenses       $ 40,951     $ 100,000     $ 200,000      
Percentage of annual increase in lease payment     3.00% 3.00%                  
Lease expiration date     Jan. 31, 2023 Jan. 31, 2023                  
Lease renewal option     5 years 5 years                  
Reimbursement amount received for tenant improvements     $ 56,325                    
Operating lease, current liabilities                       900,000  
Operating lease, non-current liabilities                       $ 2,600,000