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Collaborations and Licensing Arrangements - Additional Information (Detail 1) - USD ($)
$ in Millions
May 31, 2018
Dec. 31, 2016
Collaboration and License Agreement | Receptor | Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date: 2017-01-01    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]    
Deferred revenue - nonrefundable license fee   $ 1.0
Deferred revenue recognition period   4 years
License and Distribution Agreement | Cipla Ltd | Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date: 2018-06-01    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]    
Deferred revenue - nonrefundable license fee $ 2.2  
Deferred revenue recognition period 15 years