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Description of Business and Significant Accounting Policies - Additional Information (Detail)
€ in Millions
3 Months Ended 12 Months Ended
Mar. 31, 2019
USD ($)
Contract
Dec. 31, 2018
USD ($)
Contract
Mar. 31, 2019
EUR (€)
Jan. 01, 2019
USD ($)
Jul. 01, 2013
USD ($)
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]          
Accumulated deficit $ (2,954,883,000) $ (2,940,000,000)      
Cash and cash equivalents 34,530,000 $ 71,157,000      
Short-term investments 24,764,000        
Principal amount of outstanding borrowings 101,700,000        
Loss on purchase commitments | €     € 84.1    
(“ASC”) Topic 842 – Leases          
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]          
Increase in total assets and total liabilities       $ 5,200,000  
Short-term Investments          
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]          
Gain (loss) on investments 0        
Insulin          
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]          
Loss on purchase commitments $ 94,400,000        
Loss on purchase commitments, number of new contracts recognized | Contract 0 0      
Minimum | AFREZZA product sales          
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]          
Sales return right following product expiration in months 6 months        
Maximum | AFREZZA product sales          
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]          
Sales return right following product expiration in months 12 months        
2019 notes          
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]          
Senior notes, effective interest rate 9.75%   9.75%    
Principal amount of outstanding borrowings $ 9,000,000        
Tranche B notes          
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]          
Senior notes, effective interest rate 8.75%   8.75%    
Principal amount of outstanding borrowings $ 2,500,000        
Deerfield | Minimum          
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]          
Available amount of credit facility under covenant restrictions for each quarter end after current fiscal   $ 25,000,000      
Deerfield | 2019 notes          
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]          
Senior notes, effective interest rate 9.75%   9.75%    
Principal amount of outstanding borrowings         $ 160,000,000
Deerfield | Tranche B notes          
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items]          
Senior notes, effective interest rate 8.75%   8.75%