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Schedule of Adoption of New Revenue Guidance Impact on Condensed Consolidated Balance sheet (Detail) - USD ($)
$ in Thousands
Sep. 30, 2018
Jan. 01, 2018
Dec. 31, 2017
ASSETS      
Accounts receivable, net $ 2,752   $ 2,789
Deferred costs from commercial product sales     405
Liabilities      
Accrued expenses and other current liabilities 13,434   12,449
Deferred revenue, net     3,038
Stockholders' deficit:      
Accumulated deficit (2,930,249)   $ (2,854,898)
Accounting Standards Update 2014-09      
ASSETS      
Accounts receivable, net   $ 2,678  
Liabilities      
Accrued expenses and other current liabilities   13,098  
Stockholders' deficit:      
Accumulated deficit   (2,853,025)  
Adjustments | Accounting Standards Update 2014-09      
ASSETS      
Accounts receivable, net 417 (111)  
Deferred costs from commercial product sales 763 (405)  
Liabilities      
Accrued expenses and other current liabilities (588) 649  
Deferred revenue, net 3,601 (3,038)  
Stockholders' deficit:      
Accumulated deficit (1,833) $ 1,873  
Balances Without Adoption of Topic 606 | Accounting Standards Update 2014-09      
ASSETS      
Accounts receivable, net 3,169    
Deferred costs from commercial product sales 763    
Liabilities      
Accrued expenses and other current liabilities 12,846    
Deferred revenue, net 3,601    
Stockholders' deficit:      
Accumulated deficit $ (2,932,082)